Haplotype analyses of haemoglobin C and haemoglobin S and the dynamics of the evolutionary response to malaria in Kassena-Nankana District of Ghana.
Haemoglobin S (HbS) and C (HbC) are variants of the HBB gene which both protect against malaria. It is not clear, however, how these two alleles have evolved in the West African countries where they co-exist at high frequencies. Here we use haplotypic signatures of selection to investigate the evolu...
Váldodahkkit: | Ghansah, A, Rockett, K, Clark, T, Wilson, MD, Koram, K, Oduro, A, Amenga-Etego, L, Anyorigiya, T, Hodgson, A, Milligan, P, Rogers, W, Kwiatkowski, D |
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Materiálatiipa: | Journal article |
Giella: | English |
Almmustuhtton: |
2012
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Geahča maid
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Haplotype analyses of haemoglobin C and haemoglobin S and the dynamics of the evolutionary response to malaria in Kassena-Nankana District of Ghana.
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