Mapping immune variation and var gene switching in naive hosts infected with Plasmodium falciparum

Mapping immune variation and var gene switching in naive hosts infected with Plasmodium falciparum

Falciparum malaria is clinically heterogeneous and the relative contribution of parasite and host in shaping disease severity remains unclear. We explored the interaction between inflammation and parasite variant surface antigen (VSA) expression, asking whether this relationship underpins the variat...

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Bibliographische Detailangaben
Hauptverfasser: Milne, K, Ivens, A, Reid, AJ, Lotkowska, ME, O'Toole, A, Sankaranarayanan, G, Munoz Sandoval, D, Nahrendorf, W, Regnault, C, Edwards, NJ, Silk, SE, Payne, RO, Minassian, AM, Venkatraman, N, Sanders, MJ, Hill, AV, Barrett, M, Berriman, M, Draper, SJ, Rowe, JA, Spence, PJ
Format: Journal article
Sprache:English
Veröffentlicht: eLife Sciences Publications 2021

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