Multiplexed analysis of chromosome conformation at vastly improved sensitivity

Methods for analyzing chromosome conformation in mammalian cells are either low resolution or low throughput and are technically challenging. In next-generation (NG) Capture-C, we have redesigned the Capture-C method to achieve unprecedented levels of sensitivity and reproducibility. NG Capture-C ca...

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Detalhes bibliográficos
Main Authors: Davies, J, Telenius, J, McGowan, S, Roberts, N, Taylor, S, Higgs, D, Hughes, J
Formato: Journal article
Idioma:English
Publicado em: Nature Research 2015