Association of the influenza virus RNA polymerase subunit PB2 with the host chaperonin CCT.
The RNA polymerase of influenza A virus is a host range determinant and virulence factor. In particular, the PB2 subunit of the RNA polymerase has been implicated as a crucial factor that affects cell tropism as well as virulence in animal models. These findings suggest that host factors associating...
Hauptverfasser: | Fislová, T, Thomas, B, Graef, K, Fodor, E |
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Format: | Journal article |
Sprache: | English |
Veröffentlicht: |
2010
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