Association of the influenza virus RNA polymerase subunit PB2 with the host chaperonin CCT.

Association of the influenza virus RNA polymerase subunit PB2 with the host chaperonin CCT.

The RNA polymerase of influenza A virus is a host range determinant and virulence factor. In particular, the PB2 subunit of the RNA polymerase has been implicated as a crucial factor that affects cell tropism as well as virulence in animal models. These findings suggest that host factors associating...

Полное описание

Библиографические подробности
Главные авторы:	Fislová, T, Thomas, B, Graef, K, Fodor, E
Формат:	Journal article
Язык:	English
Опубликовано:	2010

Схожие документы

The PB2 subunit of the influenza A virus RNA polymerase is imported into the mitochondrial matrix
по: Long, J, и др.
Опубликовано: (2016)

The PA subunit is required for efficient nuclear accumulation of the PB1 subunit of the influenza A virus RNA polymerase complex.
по: Fodor, E, и др.
Опубликовано: (2004)

Chaperonin TRiC/CCT subunit CCT7 is involved in the replication of canine parvovirus in F81 cells
по: Xia Su, и др.
Опубликовано: (2024-02-01)

Assembly and substrate recognition properties of human CCT subunits of the TRiC chaperonin
по: Sergeeva, Oksana A
Опубликовано: (2015)

The PB2 subunit of the influenza virus RNA polymerase affects virulence by interacting with the mitochondrial antiviral signaling protein and inhibiting expression of beta interferon.
по: Graef, K, и др.
Опубликовано: (2010)

Folding for the Immune Synapse: CCT Chaperonin and the Cytoskeleton
по: Noa Beatriz Martín-Cófreces, и др.
Опубликовано: (2021-04-01)

The host-dependent interaction of alpha-importins with influenza PB2 polymerase subunit is required for virus RNA replication.
по: Patricia Resa-Infante, и др.
Опубликовано: (2008-01-01)

Exogenous delivery of chaperonin subunit fragment ApiCCT1 modulates mutant Huntingtin cellular phenotypes
по: Sontag, Emily M., и др.
Опубликовано: (2013)

The role of the influenza virus RNA polymerase in host shut-off.
по: Vreede, F, и др.
Опубликовано: (2010)

Chaperonin containing T-complex polypeptide subunit eta (CCT-eta) is a specific regulator of fibroblast motility and contractility.
по: Latha Satish, и др.
Опубликовано: (2010-04-01)

Two aromatic residues in the PB2 subunit of influenza A RNA polymerase are crucial for cap binding.
по: Fechter, P, и др.
Опубликовано: (2003)

Characterization of the interaction between the influenza A virus polymerase subunit PB1 and the host nuclear import factor Ran-binding protein 5.
по: Hutchinson, E, и др.
Опубликовано: (2011)

The malaria parasite chaperonin containing TCP-1 (CCT) complex: Data integration with other CCT proteomes
по: Mark D. Wilkinson, и др.
Опубликовано: (2022-12-01)

Muscle Histopathological Abnormalities in a Patient With a CCT5 Mutation Predicted to Affect the Apical Domain of the Chaperonin Subunit
по: Federica Scalia, и др.
Опубликовано: (2022-06-01)

Native mass spectrometry analyses of chaperonin complex TRiC/CCT reveal subunit N-terminal processing and re-association patterns
по: Miranda P. Collier, и др.
Опубликовано: (2021-06-01)

Interplay between influenza virus and the host RNA polymerase II transcriptional machinery
по: Walker, A, и др.
Опубликовано: (2019)

Association of the influenza A virus RNA-dependent RNA polymerase with cellular RNA polymerase II.
по: Engelhardt, O, и др.
Опубликовано: (2005)

Crystal structure of the open conformation of the mammalian chaperonin CCT in complex with tubulin.
по: Muñoz, I, и др.
Опубликовано: (2011)

Structural and functional characterisation of the group II chaperonin CCT/TRiC
по: Kelly, J
Опубликовано: (2020)

Modulation of STAT3 folding and function by TRiC/CCT chaperonin.
по: Moses Kasembeli, и др.
Опубликовано: (2014-04-01)

Mutational analysis of the PA and PB2 subunits of the influenza RNA polymerase complex leads to new insights into function
по: Fodor, E, и др.
Опубликовано: (2004)

Quantitative analysis of the impact of a human pathogenic mutation on the CCT5 chaperonin subunit using a proxy archaeal ortholog
по: Dario Spigolon, и др.
Опубликовано: (2017-12-01)

A cluster of conserved basic amino acids near the C-terminus of the PB1 subunit of the influenza virus RNA polymerase is involved in the regulation of viral transcription.
по: Kerry, P, и др.
Опубликовано: (2008)

The C-terminal domains of the PB2 subunit of the influenza A virus RNA polymerase directly interact with cellular GTPase Rab11a
по: Veler, H, и др.
Опубликовано: (2022)

Avian Chaperonin Containing TCP1 Subunit 5 Supports Influenza A Virus Replication by Interacting With Viral Nucleoprotein, PB1, and PB2 Proteins
по: Xiaohan Zhang, и др.
Опубликовано: (2020-10-01)

The chaperonin CCT8 controls proteostasis essential for T cell maturation, selection, and function
по: Oftedal, BE, и др.
Опубликовано: (2021)

Chaperonin TRiC/CCT supports mitotic exit and entry into endocycle in Drosophila.
по: Yuya Ohhara, и др.
Опубликовано: (2019-04-01)

Asymmetry in the function and dynamics of the cytosolic group II chaperonin CCT/TRiC.
по: Yohei Y Yamamoto, и др.
Опубликовано: (2017-01-01)

Structural and functional analysis of the role of the chaperonin CCT in mTOR complex assembly
по: Jorge Cuéllar, и др.
Опубликовано: (2019-06-01)

The chaperonin CCT8 controls proteostasis essential for T cell maturation, selection, and function
по: Bergithe E. Oftedal, и др.
Опубликовано: (2021-06-01)

Molecular basis of host-adaptation interactions between influenza virus polymerase PB2 subunit and ANP32A
по: Aldo R. Camacho-Zarco, и др.
Опубликовано: (2020-07-01)

RNA-free and ribonucleoprotein-associated influenza virus polymerases directly bind the serine-5 phosphorylated carboxyl-terminal domain of host RNA polymerase II
по: Fodor, E, и др.
Опубликовано: (2016)

Structural and functional characterization of the interaction between the influenza A virus RNA polymerase and the CTD of host RNA polymerase II
по: Keown, J, и др.
Опубликовано: (2024)

Interaction of polymerase subunit PB2 and NP with importin alpha1 is a determinant of host range of influenza A virus.
по: Gülsah Gabriel, и др.
Опубликовано: (2008-02-01)

Chaperonin CCT controls extracellular vesicle production and cell metabolism through kinesin dynamics
по: Amelia Rojas‐Gómez, и др.
Опубликовано: (2023-06-01)

TRiC/CCT chaperonin is required for the folding and inhibitory effect of WDTC1 on adipogenesis
по: Wen-Shuai Tang, и др.
Опубликовано: (2023-08-01)

Mechanisms and functional implications of the degradation of host RNA polymerase II in influenza virus infected cells.
по: Vreede, F, и др.
Опубликовано: (2010)

Influenza virus RNA polymerase: insights into the mechanisms of viral RNA synthesis
по: Fodor, E, и др.
Опубликовано: (2016)

The role of the PB2 627-domain in influenza A virus polymerase function
по: Nilsson, B, и др.
Опубликовано: (2017)

The Influenza Virus RNA-Polymerase and the Host RNA-Polymerase II: RPB4 Is Targeted by a PB2 Domain That Is Involved in Viral Transcription
по: Jessica Morel, и др.
Опубликовано: (2022-03-01)