Arterial spin labeling for cerebral perfusion and angiography
Arterial spin labeling (ASL) is an MRI technique that was first proposed a quarter of a century ago. It offers the prospect of non-invasive quantitative measurement of cerebral perfusion, making it potentially very useful for research and clinical studies, particularly where multiple longitudinal me...
| Päätekijät: | , , |
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| Aineistotyyppi: | Journal article |
| Julkaistu: |
SAGE Publications
2017
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| _version_ | 1826268577812971520 |
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| author | Jezzard, P Chappell, M Okell, T |
| author_facet | Jezzard, P Chappell, M Okell, T |
| author_sort | Jezzard, P |
| collection | OXFORD |
| description | Arterial spin labeling (ASL) is an MRI technique that was first proposed a quarter of a century ago. It offers the prospect of non-invasive quantitative measurement of cerebral perfusion, making it potentially very useful for research and clinical studies, particularly where multiple longitudinal measurements are required. However, it has suffered from a number of challenges, including a relatively low signal-to-noise ratio, and a confusing number of sequence variants, thus hindering its clinical uptake. Recently, however, there has been a consensus adoption of an accepted acquisition and analysis framework for ASL, and thus a better penetration onto clinical MRI scanners. Here, we review the basic concepts in ASL, and describe the current state-of-the-art acquisition and analysis approaches, and the versatility of the method to perform both quantitative cerebral perfusion measurement, along with quantitative cerebral angiographic measurement. |
| first_indexed | 2024-03-06T21:11:50Z |
| format | Journal article |
| id | oxford-uuid:3e7157c0-ad84-4c78-a93c-f442a70eb438 |
| institution | University of Oxford |
| last_indexed | 2024-03-06T21:11:50Z |
| publishDate | 2017 |
| publisher | SAGE Publications |
| record_format | dspace |
| spelling | oxford-uuid:3e7157c0-ad84-4c78-a93c-f442a70eb4382022-03-26T14:25:31ZArterial spin labeling for cerebral perfusion and angiographyJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:3e7157c0-ad84-4c78-a93c-f442a70eb438Symplectic Elements at OxfordSAGE Publications2017Jezzard, PChappell, MOkell, TArterial spin labeling (ASL) is an MRI technique that was first proposed a quarter of a century ago. It offers the prospect of non-invasive quantitative measurement of cerebral perfusion, making it potentially very useful for research and clinical studies, particularly where multiple longitudinal measurements are required. However, it has suffered from a number of challenges, including a relatively low signal-to-noise ratio, and a confusing number of sequence variants, thus hindering its clinical uptake. Recently, however, there has been a consensus adoption of an accepted acquisition and analysis framework for ASL, and thus a better penetration onto clinical MRI scanners. Here, we review the basic concepts in ASL, and describe the current state-of-the-art acquisition and analysis approaches, and the versatility of the method to perform both quantitative cerebral perfusion measurement, along with quantitative cerebral angiographic measurement. |
| spellingShingle | Jezzard, P Chappell, M Okell, T Arterial spin labeling for cerebral perfusion and angiography |
| title | Arterial spin labeling for cerebral perfusion and angiography |
| title_full | Arterial spin labeling for cerebral perfusion and angiography |
| title_fullStr | Arterial spin labeling for cerebral perfusion and angiography |
| title_full_unstemmed | Arterial spin labeling for cerebral perfusion and angiography |
| title_short | Arterial spin labeling for cerebral perfusion and angiography |
| title_sort | arterial spin labeling for cerebral perfusion and angiography |
| work_keys_str_mv | AT jezzardp arterialspinlabelingforcerebralperfusionandangiography AT chappellm arterialspinlabelingforcerebralperfusionandangiography AT okellt arterialspinlabelingforcerebralperfusionandangiography |