The pathophysiology of the intervertebral disk
After a review of disk structure, the pivotal role of disk cells in producing and renewing the extracellular disk matrix is emphasized. Disk cells nutrition rely on nutrients that diffuse through the vertebral endplates. Microelectrode methods have been developed to study nutrient diffusion and endp...
Автори: | , , , , |
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Формат: | Journal article |
Мова: | French |
Опубліковано: |
2001
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_version_ | 1826268595372425216 |
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author | Bibby, S Jones, D Lee, R Yu, J Urban, J |
author_facet | Bibby, S Jones, D Lee, R Yu, J Urban, J |
author_sort | Bibby, S |
collection | OXFORD |
description | After a review of disk structure, the pivotal role of disk cells in producing and renewing the extracellular disk matrix is emphasized. Disk cells nutrition rely on nutrients that diffuse through the vertebral endplates. Microelectrode methods have been developed to study nutrient diffusion and endplate permeability. Mechanical stimuli modify disk cell activity. Scoliosis is associated with decreased endplate permeability, a factor that may play a role in disk degeneration and scoliosis progression. © 2001 Éditions scientifiques et médicales Elsevier SAS. |
first_indexed | 2024-03-06T21:12:06Z |
format | Journal article |
id | oxford-uuid:3e87f31d-5a27-4aee-81d9-fe0f731b7ca8 |
institution | University of Oxford |
language | French |
last_indexed | 2024-03-06T21:12:06Z |
publishDate | 2001 |
record_format | dspace |
spelling | oxford-uuid:3e87f31d-5a27-4aee-81d9-fe0f731b7ca82022-03-26T14:26:06ZThe pathophysiology of the intervertebral diskJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:3e87f31d-5a27-4aee-81d9-fe0f731b7ca8FrenchSymplectic Elements at Oxford2001Bibby, SJones, DLee, RYu, JUrban, JAfter a review of disk structure, the pivotal role of disk cells in producing and renewing the extracellular disk matrix is emphasized. Disk cells nutrition rely on nutrients that diffuse through the vertebral endplates. Microelectrode methods have been developed to study nutrient diffusion and endplate permeability. Mechanical stimuli modify disk cell activity. Scoliosis is associated with decreased endplate permeability, a factor that may play a role in disk degeneration and scoliosis progression. © 2001 Éditions scientifiques et médicales Elsevier SAS. |
spellingShingle | Bibby, S Jones, D Lee, R Yu, J Urban, J The pathophysiology of the intervertebral disk |
title | The pathophysiology of the intervertebral disk |
title_full | The pathophysiology of the intervertebral disk |
title_fullStr | The pathophysiology of the intervertebral disk |
title_full_unstemmed | The pathophysiology of the intervertebral disk |
title_short | The pathophysiology of the intervertebral disk |
title_sort | pathophysiology of the intervertebral disk |
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