RelB/p50 regulates TNF production in LPS-stimulated dendritic cells and macrophages.
Dendritic cells (DCs) and macrophages are effective antigen-presenting cells, and DCs, once matured, have the ability to potently activate naïve T cells. While the canonical p65/p50 NF-κB pathway seems to have an important role during LPS-stimulation of these cells, the specific contribution of the...
Autori principali: | Gasparini, C, Foxwell, B, Feldmann, M |
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Natura: | Journal article |
Lingua: | English |
Pubblicazione: |
2013
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