SYNTHESIS FROM D-GLUCOSE OF 1,5-DIDEOXY-1,5-IMINO-L-FUCITOL, A POTENT ALPHA-L-FUCOSIDASE INHIBITOR
1,5-Dideoxy-1,5-imino-L-fucitol (1), synthesised from methyl α-D-glucopyranoside, is a potent competitive inhibitor of the hydrolysis of p-nitrophenyl α-L-fucopyranoside catalysed by α-L-fucosidase (ex. bovine epididymis) causing 50% inhibition of enzymic activity at 2.5 × 10...
| Principais autores: | , , |
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| Formato: | Journal article |
| Idioma: | English |
| Publicado em: |
1985
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| _version_ | 1826268621985284096 |
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| author | Fleet, G Shaw, A Evans, S Evans, S |
| author_facet | Fleet, G Shaw, A Evans, S Evans, S |
| author_sort | Fleet, G |
| collection | OXFORD |
| description | 1,5-Dideoxy-1,5-imino-L-fucitol (1), synthesised from methyl α-D-glucopyranoside, is a potent competitive inhibitor of the hydrolysis of p-nitrophenyl α-L-fucopyranoside catalysed by α-L-fucosidase (ex. bovine epididymis) causing 50% inhibition of enzymic activity at 2.5 × 10 -8 M. |
| first_indexed | 2024-03-06T21:12:31Z |
| format | Journal article |
| id | oxford-uuid:3eaa444b-91d2-4fdc-a8bc-47de8ca32b0d |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T21:12:31Z |
| publishDate | 1985 |
| record_format | dspace |
| spelling | oxford-uuid:3eaa444b-91d2-4fdc-a8bc-47de8ca32b0d2022-03-26T14:26:53ZSYNTHESIS FROM D-GLUCOSE OF 1,5-DIDEOXY-1,5-IMINO-L-FUCITOL, A POTENT ALPHA-L-FUCOSIDASE INHIBITORJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:3eaa444b-91d2-4fdc-a8bc-47de8ca32b0dEnglishSymplectic Elements at Oxford1985Fleet, GShaw, AEvans, SEvans, S1,5-Dideoxy-1,5-imino-L-fucitol (1), synthesised from methyl α-D-glucopyranoside, is a potent competitive inhibitor of the hydrolysis of p-nitrophenyl α-L-fucopyranoside catalysed by α-L-fucosidase (ex. bovine epididymis) causing 50% inhibition of enzymic activity at 2.5 × 10 -8 M. |
| spellingShingle | Fleet, G Shaw, A Evans, S Evans, S SYNTHESIS FROM D-GLUCOSE OF 1,5-DIDEOXY-1,5-IMINO-L-FUCITOL, A POTENT ALPHA-L-FUCOSIDASE INHIBITOR |
| title | SYNTHESIS FROM D-GLUCOSE OF 1,5-DIDEOXY-1,5-IMINO-L-FUCITOL, A POTENT ALPHA-L-FUCOSIDASE INHIBITOR |
| title_full | SYNTHESIS FROM D-GLUCOSE OF 1,5-DIDEOXY-1,5-IMINO-L-FUCITOL, A POTENT ALPHA-L-FUCOSIDASE INHIBITOR |
| title_fullStr | SYNTHESIS FROM D-GLUCOSE OF 1,5-DIDEOXY-1,5-IMINO-L-FUCITOL, A POTENT ALPHA-L-FUCOSIDASE INHIBITOR |
| title_full_unstemmed | SYNTHESIS FROM D-GLUCOSE OF 1,5-DIDEOXY-1,5-IMINO-L-FUCITOL, A POTENT ALPHA-L-FUCOSIDASE INHIBITOR |
| title_short | SYNTHESIS FROM D-GLUCOSE OF 1,5-DIDEOXY-1,5-IMINO-L-FUCITOL, A POTENT ALPHA-L-FUCOSIDASE INHIBITOR |
| title_sort | synthesis from d glucose of 1 5 dideoxy 1 5 imino l fucitol a potent alpha l fucosidase inhibitor |
| work_keys_str_mv | AT fleetg synthesisfromdglucoseof15dideoxy15iminolfucitolapotentalphalfucosidaseinhibitor AT shawa synthesisfromdglucoseof15dideoxy15iminolfucitolapotentalphalfucosidaseinhibitor AT evanss synthesisfromdglucoseof15dideoxy15iminolfucitolapotentalphalfucosidaseinhibitor AT evanss synthesisfromdglucoseof15dideoxy15iminolfucitolapotentalphalfucosidaseinhibitor |