SYNTHESIS FROM D-GLUCOSE OF 1,5-DIDEOXY-1,5-IMINO-L-FUCITOL, A POTENT ALPHA-L-FUCOSIDASE INHIBITOR

SYNTHESIS FROM D-GLUCOSE OF 1,5-DIDEOXY-1,5-IMINO-L-FUCITOL, A POTENT ALPHA-L-FUCOSIDASE INHIBITOR

1,5-Dideoxy-1,5-imino-L-fucitol (1), synthesised from methyl α-D-glucopyranoside, is a potent competitive inhibitor of the hydrolysis of p-nitrophenyl α-L-fucopyranoside catalysed by α-L-fucosidase (ex. bovine epididymis) causing 50% inhibition of enzymic activity at 2.5 × 10...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς:	Fleet, G, Shaw, A, Evans, S
Μορφή:	Journal article
Γλώσσα:	English
Έκδοση:	1985

Παρόμοια τεκμήρια

SHORT EFFICIENT SYNTHESIS OF THE ALPHA-L-FUCOSIDASE INHIBITOR, DEOXYFUCONOJIRIMYCIN [1,5-DIDEOXY-1,5-IMINO-L-FUCITOL] FROM D-LYXONOLACTONE
ανά: Fleet, G, κ.ά.
Έκδοση: (1989)

SYNTHESIS OF 1,5-DIDEOXY-3-O-(ALPHA-D-MANNOPYRANOSYL)-1,5-IMINO-D-MANNITOL AND 1,5-DIDEOXY-3-O-(ALPHA-D-GLUCOPYRANOSYL)-1,5-IMINO-D-MANNITOL - POWERFUL INHIBITORS OF ENDOMANNOSIDASE
ανά: Ardron, H, κ.ά.
Έκδοση: (1993)

Hydroxymethyl-Branched Piperidines from Hydroxymethyl-Branched Lactones: Synthesis and Biological Evaluation of 1,5-Dideoxy-2-C-hydroxymethyl-1,5-imino-D-mannitol, 1,5-Dideoxy-2-C-hydroxymethyl-1,5-imino-L-gulitol and 1,5-Dideoxy-2-C-hydroxymethyl-1,5-imino-D-talitol
ανά: Soengas, R, κ.ά.
Έκδοση: (2012)

SYNTHESES OF 1,5-DIDEOXY-1,5-IMINO-D-MANNITOL FROM D-MANNOSE AND FROM D-GLUCOSE
ανά: Fleet, G, κ.ά.
Έκδοση: (1984)

Inhibition of the alpha-L-arabinofuranosidase III of Monilinia fructigena by 1,4-dideoxy-1,4-imino-L-threitol and 1,4-dideoxy-1,4-imino-L-arabinitol.
ανά: Axamawaty, M, κ.ά.
Έκδοση: (1990)

POTENT COMPETITIVE-INHIBITION OF ALPHA-GALACTOSIDASE AND ALPHA-GLUCOSIDASE ACTIVITY BY 1,4-DIDEOXY-1,4-IMINOPENTITOLS - SYNTHESES OF 1,4-DIDEOXY-1,4-IMINO-D-LYXITOL AND OF BOTH ENANTIOMERS OF 1,4-DIDEOXY-1,4-IMINOARABINITOL
ανά: Fleet, G, κ.ά.
Έκδοση: (1985)

DESIGN SYNTHESIS AND PRELIMINARY EVALUATION OF A POTENT ALPHA-MANNOSIDASE INHIBITOR - 1,4-DIDEOXY-1,4-IMINO-D-MANNITOL
ανά: Fleet, G, κ.ά.
Έκδοση: (1984)

THE SYNTHESIS FROM D-XYLOSE OF THE POTENT AND SPECIFIC ENANTIOMERIC GLUCOSIDASE INHIBITORS, 1,4-DIDEOXY-1,4-IMINO-D-ARABINITOL AND 1,4-DIDEOXY-1,4-IMINO-L-ARABINITOL
ανά: Fleet, G, κ.ά.
Έκδοση: (1986)

Green synthesis of 1,5-dideoxy-1,5-imino-ribitol and 1,5-dideoxy-1,5-imino-dl-arabinitol from natural d-sugars over Au/Al2O3 and SO4 2−/Al2O3 catalysts
ανά: Hongjian Gao, κ.ά.
Έκδοση: (2021-08-01)

SYNTHESIS FROM D-MANNOSE OF 1,4-DIDEOXY-1,4-IMINO-L-RIBITOL AND OF THE ALPHA-MANNOSIDASE INHIBITOR 1,4-DIDEOXY-1,4-IMINO-D-TALITOL
ανά: Fleet, G, κ.ά.
Έκδοση: (1988)

Looking glass inhibitors: synthesis of a potent naringinase inhibitor L-DIM [1,4-dideoxy-1,4-imino-L-mannitol], the enantiomer of DIM [1,4-dideoxy-1,4-imino-D-mannitol] a potent alpha-D-mannosidase inhibitor
ανά: Hakansson, A, κ.ά.
Έκδοση: (2007)

N-Benzyl-1, 3-dideoxy-1, 3-imino-L-xylitol
ανά: Jenkinson, S, κ.ά.
Έκδοση: (2011)

INHIBITION OF ALPHA-MANNOSIDASE ACTIVITY BY 1,4-DIDEOXY-1,4-IMINO-D-MANNITOL
ανά: Elbein, A, κ.ά.
Έκδοση: (1985)

1-De-oxy-d-galactitol (l-fucitol).
ανά: Jenkinson, S, κ.ά.
Έκδοση: (2008)

Looking glass inhibitors: both enantiomeric N-benzyl derivatives of 1,4-dideoxy-1,4-imino-D-lyxitol [a potent competitive inhibitor of alpha-D-galactosidase] and of 1,4-dideoxy-1,4-imino-L-lyxitol [a weak competitive inhibitor of alpha-D-galactosidase] inhibit naringinase, an alpha-L-rhamnosidase competitively
ανά: Mercer, T, κ.ά.
Έκδοση: (2009)

3-O-Benzhydryl-2,5-dideoxy-2,5-imino-2-C-methyl-l-lyxono-1,4-lactone
ανά: David J. Watkin, κ.ά.
Έκδοση: (2008-10-01)

SYNTHESIS OF DEOXYMANNOJIRIMYCIN FAGOMINE DEOXYNOJIRIMYCIN 2-ACETAMIDO-1,5-IMINO-1,2,5-TRIDEOXY-D-MANNITOL 2-ACETAMIDO-1,5-IMINO-1,2,5-TRIDEOXY-D-GLUCITOL 2S, 3R, 4R, 5R-TRIHYDROXYPIPECOLIC ACID AND 2S, 3R, 4R, 5S-TRIHYDROXYPIPECOLIC ACID FROM METHYL 3-O-BENZYL-2,6-DIDEOXY-2,6-IMINO-ALPHA-D-MANNOFURANOSIDE
ανά: Fleet, G, κ.ά.
Έκδοση: (1987)

SYNTHESIS OF 2-ACETAMIDO-1,5-IMINO-1,2,5-TRIDEOXY-D-MANNITOL AND OF 2-ACETAMIDO-1,5-IMINO-1,2,5-TRIDEOXY-D-GLUCITOL, A POTENT AND SPECIFIC INHIBITOR OF A NUMBER OF BETA-N-ACETYLGLUCOSAMINIDASES
ανά: Fleet, G, κ.ά.
Έκδοση: (1986)

An alpha-glucoside of 1,4-dideoxy-1,4-imino-D-lyxitol with an eleven carbon side chain
ανά: Kato, A, κ.ά.
Έκδοση: (2010)

3,6-dideoxy-3,6-imino-1,2-o-isopropylidene-α-d-glucofuranose as a divergent intermediate for the synthesis of hydroxylated pyrrolidines; synthesis of 1,4 dideoxy-1,4-imino-l-gulitol,...
ανά: Fleet, G, κ.ά.
Έκδοση: (1987)

SYNTHESIS OF HOMOCHIRAL BETA-HYDROXY-ALPHA-AMINO-ACIDS [(2S,3R,4R)-3,4-DIHYDROXYPROLINE AND (2S,3R,4R)-3,4-DIHYDROXYPIPECOLIC ACID] AND OF 1,4-DIDEOXY-1,4-IMINO-D-ARABINITOL [DAB1] AND FAGOMINE [1,5-IMINO-1,2,5-TRIDEOXY-D-ARABINO-HEXITOL]
ανά: Fleet, G, κ.ά.
Έκδοση: (1990)

POLYHYDROXYLATED PYRROLIDINES FROM SUGAR LACTONES - SYNTHESIS OF 1,4-DIDEOXY-1,4-IMINO-D-GLUCITOL FROM D-GALACTONOLACTONE AND SYNTHESES OF 1,4-DIDEOXY-1,4-IMINO-D-ALLITOL, 1,4-DIDEOXY-1,4-IMINO-D-RIBITOL, AND (2S,3R,4S)-3,4-DIHYDROXYPROLINE FROM D-GULONOLACTONE
ανά: Fleet, G, κ.ά.
Έκδοση: (1988)

Inhibition of alpha-L-fucosidase by derivatives of deoxyfuconojirimycin and deoxymannojirimycin.
ανά: Winchester, B, κ.ά.
Έκδοση: (1990)

1,4-Dideoxy-1,4-imino-D-mannitol inhibits glycoprotein processing and mannosidase.
ανά: Palamarczyk, G, κ.ά.
Έκδοση: (1985)

Effects of the alpha-mannosidase inhibitors, 1,4-dideoxy-1,4-imino-D-mannitol and swainsonine, on glycoprotein catabolism in cultured macrophages.
ανά: Daniel, P, κ.ά.
Έκδοση: (1989)

Asymmetric syntheses of 2,5-dideoxy-2,5-imino-D-glucitol [(+)-DGDP] and 1,2,5-trideoxy-1-amino-2,5-imino-D-glucitol [(+)-ADGDP]
ανά: Davies, S, κ.ά.
Έκδοση: (2014)

Asymmetric syntheses of 2,5-dideoxy-2,5-imino-d-glucitol [(+)-DGDP] and 1,2,5-trideoxy-1-amino-2,5-imino-d-glucitol [(+)-ADGDP]
ανά: Davies, S, κ.ά.
Έκδοση: (2014)

Synthesis of homochiral β-hydroxy-α-aminoacids [(2S,3R,4R)-3,4-dihydroxyproline and (2S,3R,4R)-3,4-dihydroxypipecolic aicd] and of 1,4-dideoxy-1,4-imino-D-arabinitol [DAB1] and fagomine [1,5-imino-1,2,5-trideoxy-D-arabino-hexitol]
ανά: Fleet, G, κ.ά.
Έκδοση: (1990)

Synthesis from D-altrose of (5R,6R,7R,8S)-5,7-dihydroxy-8-hydroxymethylconidine and 2,4-dideoxy-2,4-imino-D-glucitol, azetidine analogues of swainsonine and 1,4-dideoxy-1,4-imino-D-mannitol.
ανά: Araújo, N, κ.ά.
Έκδοση: (2012)

ALPHA-HOMONOJIRIMYCIN [2,6-DIDEOXY-2,6-IMINO-D-GLYCERO-L-GULO-HEPTITOL] FROM OMPHALEA-DIANDRA L - ISOLATION AND GLUCOSIDASE INHIBITION
ανά: Kite, G, κ.ά.
Έκδοση: (1988)

2-deoxy-L-ribose from an L-arabinono-1,5-lactone
ανά: Stewart, A, κ.ά.
Έκδοση: (2002)

N-(2-Carboxyethyl)-2,5-dideoxy-2,5-imino-D-mannonic acid [(3R,4R,5R)-1-(2-carboxyethyl)-3,4-dihydroxy-5-hydroxymethyl-L-proline]
ανά: Edgeley, D, κ.ά.
Έκδοση: (2012)

SYNTHESIS FROM D-LYXONOLACTONE OF 1,4-DIDEOXY-1,4-IMINO-L-ARABINITOL, A GLUCOSIDASE INHIBITOR WITH INVITRO ANTIVIRAL ACTIVITY
ανά: Behling, J, κ.ά.
Έκδοση: (1993)

3,6-DIDEOXY-3,6-IMINO-1,2-O-ISOPROPYLIDENE-ALPHA-D-GLUCOFURANOSE AS A DIVERGENT INTERMEDIATE FOR THE SYNTHESIS OF HYDROXYLATED PYRROLIDINES - SYNTHESIS OF 1,4-DIDEOXY-1,4-IMINO-L-GULITOL, 1,4-DIDEOXY-1,4-IMINO-D-LYXITOL, 2S,3S,4R-3,4-DIHYDROXYPROLINE AND (1S,2R,8S,8AR)-1,2,8-TRIHYDROXYOCTAHYDROINDOLIZINE [8-EPI-SWAINSONINE] - X-RAY CRYSTAL-STRUCTURE OF (1S,2R,8S,8AR)-1,2,8-TRIHYDROXY-5-OXO-OCTAHYDROINDOLIZINE
ανά: Austin, G, κ.ά.
Έκδοση: (1987)

Methyl 2,4-anhydro-5-azido-5,6-dideoxy-L-altronate
ανά: Watkin, D, κ.ά.
Έκδοση: (2004)

Novel alpha-L-fucosidase inhibitors from the bark of Angylocalyx pynaertii (Leguminosae).
ανά: Asano, N, κ.ά.
Έκδοση: (2001)

IMINOHEPTITOLS AS GLYCOSIDASE INHIBITORS - SYNTHESIS OF AND SPECIFIC ALPHA-L-FUCOSIDASE INHIBITION BY BETA-L-HOMOFUCONOJIRIMYCIN AND 1-BETA-C-SUBSTITUTED DEOXYMANNOJIRIMYCINS
ανά: Fleet, G, κ.ά.
Έκδοση: (1989)

SYNTHESIS OF THE ALPHA-MANNOSIDASE INHIBITORS SWAINSONINE [(1S, 2R, 8R, 8AR)-1,2,8-TRIHYDROXYOCTAHYDROINDOLIZINE] AND 1,4-DIDEOXY-1,4-IMINO-D-MANNITOL FROM MANNOSE
ανά: Bashyal, B, κ.ά.
Έκδοση: (1987)

Isopropyl 6-amino-2,5-anhydro-3,6-dideoxy-6-N-(2,5-anhydro-6-azido-3,6-dideoxy-L-arabino-hexonyl)-L-arabino-hexonate
ανά: Cooper, R, κ.ά.
Έκδοση: (2003)

Inhibition of fucosyl transferase and fucosidase by a rigid bicyclic mimic of alpha-L-fucose
ανά: Beacham, A, κ.ά.
Έκδοση: (1998)