The Small Non-coding Vault RNA1-1 Acts as a Riboregulator of Autophagy

Vault RNAs (vtRNA) are small non-coding RNAs transcribed by RNA polymerase III found in many eukaryotes. Although they have been linked to drug resistance, apoptosis, and viral replication, their molecular functions remain unclear. Here, we show that vault RNAs directly bind the autophagy receptor s...

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Dettagli Bibliografici
Autori principali: Horos, R, Büscher, M, Kleinendorst, R, Alleaume, A-M, Tarafder, AK, Schwarzl, T, Dziuba, D, Tischer, C, Zielonka, EM, Adak, A, Castello, A, Huber, W, Sachse, C, Hentze, MW
Natura: Journal article
Lingua:English
Pubblicazione: Cell Press 2019