Dynamics of HBsAg clearance in a UK cohort of chronic HBV infection

Hepatitis B surface antigen (HBsAg) has recently gained traction as a biomarker that may provide prognostic information and inform treatment decisions in chronic hepatitis B virus (HBV) infection. It may be particularly useful when HBV DNA levels are low and therefore difficult to quantify accuratel...

詳細記述

書誌詳細
主要な著者: Downs, L, Patel, M, Ansari, M, McNaughton, A, Smith, D, Andersson, M, Barnes, E, Jeffery, K, Matthews, P
フォーマット: Conference item
出版事項: Elsevier 2018
その他の書誌記述
要約:Hepatitis B surface antigen (HBsAg) has recently gained traction as a biomarker that may provide prognostic information and inform treatment decisions in chronic hepatitis B virus (HBV) infection. It may be particularly useful when HBV DNA levels are low and therefore difficult to quantify accurately, either as a result of treatment or natural immune control of the virus. There are few published descriptions of the kinetics of HBV clearance, and most existing data come from Asia. We therefore set out to identify adults who cleared HBsAg in a UK cohort, to characterise those who clear, and to describe the dynamics of HBsAg clearance.