Detecting intratumoral heterogeneity of EGFR activity by liposome-based in vivo transfection of a fluorescent biosensor.

Detecting intratumoral heterogeneity of EGFR activity by liposome-based in vivo transfection of a fluorescent biosensor.

Despite decades of research in the epidermal growth factor receptor (EGFR) signalling field, and many targeted anti-cancer drugs that have been tested clinically, the success rate for these agents in the clinic is low, particularly in terms of the improvement of overall survival. Intratumoral hetero...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser:	Weitsman, G, Mitchell, NJ, Evans, R, Cheung, A, Kalber, TL, Bofinger, R, Fruhwirth, GO, Keppler, M, Wright, ZVF, Barber, PR, Gordon, P, de Koning, T, Wulaningsih, W, Vojnovic, B, Ameer-Beg, S, Lythgoe, M, Arnold, JN, Årstad, E, Festy, F, Hailes, HC, Tabor, AB, Ng, T
Format:	Journal article
Sprache:	English
Veröffentlicht:	2018

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