Spectroelectrochemical and computational studies on the mechanism of hypoxia selectivity of copper radiopharmaceuticals.

Detailed chemical, spectroelectrochemical and computational studies have been used to investigate the mechanism of hypoxia selectivity of a range of copper radiopharmaceuticals. A revised mechanism involving a delicate balance between cellular uptake, intracellular reduction, reoxidation, protonatio...

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Detalles Bibliográficos
Main Authors: Holland, J, Barnard, P, Collison, D, Dilworth, JR, Edge, R, Green, J, McInnes, E
Formato: Journal article
Idioma:English
Publicado: 2008