E2F-7 couples DNA damage-dependent transcription with the DNA repair process.

The cellular response to DNA damage, mediated by the DNA repair process, is essential in maintaining the integrity and stability of the genome. E2F-7 is an atypical member of the E2F family with a role in negatively regulating transcription and cell cycle progression under DNA damage. Surprisingly,...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Zalmas, L, Coutts, A, Helleday, T, La Thangue, N
Format: Journal article
Sprache:English
Veröffentlicht: Taylor and Francis 2013