Substrate versus inhibitor dynamics of P-glycoprotein.
By far the most studied multidrug resistance protein is P-glycoprotein. Despite recent structural data, key questions about its function remain. P-glycoprotein (P-gp) is flexible and undergoes large conformational changes as part of its function and in this respect, details not only of the export cy...
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2013
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