Clustered DNA damage, influence on damage excision by XRS5 nuclear extracts and Escherichia coli Nth and Fpg proteins.
Ionizing radiation and radiomimetic anticancer agents induce clustered DNA damage, which are thought to reflect the biological severity. Escherichia coli Nth and Fpg and nuclear extracts from XRS5, a Chinese hamster ovary Ku-deficient cell line, have been used to study the influence on their substra...
Váldodahkkit: | David-Cordonnier, M, Laval, J, O'Neill, P |
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Materiálatiipa: | Journal article |
Giella: | English |
Almmustuhtton: |
2000
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Geahča maid
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Recognition and kinetics for excision of a base lesion within clustered DNA damage by the Escherichia coli proteins Fpg and Nth.
Dahkki: David-Cordonnier, M, et al.
Almmustuhtton: (2001) -
Efficiency of excision of 8-oxo-guanine within DNA clustered damage by XRS5 nuclear extracts and purified human OGG1 protein.
Dahkki: David-Cordonnier, M, et al.
Almmustuhtton: (2001) -
Clustered DNA damage induced by gamma radiation in human fibroblasts (HF19), hamster (V79-4) cells and plasmid DNA is revealed as Fpg and Nth sensitive sites.
Dahkki: Gulston, M, et al.
Almmustuhtton: (2002) -
8-OxoA inhibits the incision of an AP site by the DNA glycosylases Fpg, Nth and the AP endonuclease HAP1.
Dahkki: Lomax, M, et al.
Almmustuhtton: (2005) -
Excision of 8-oxoguanine within clustered damage by the yeast OGG1 protein.
Dahkki: David-Cordonnier, M, et al.
Almmustuhtton: (2001)