Trial of chloramphenicol for meningitis in northern savanna of Africa.
In a controlled trial chloramphenicol proved as effective and much cheaper than penicillin for the treatment of group A meningococcal meningitis in Zaria, Nigeria. A short course of five days cured most patients. Adults and older children were soon able to take chloramphenicol by mouth, which reduce...
Main Authors: | , , , , , , , , , , , |
---|---|
Format: | Journal article |
Language: | English |
Published: |
1973
|
_version_ | 1826268719165210624 |
---|---|
author | Whittle, H Davidson, N Greenwood, B Warrell, D Tomkins, A Tugwell, P Zalin, A Bryceson, A Parry, E Brueton, M Duggan, M Rajković, A |
author_facet | Whittle, H Davidson, N Greenwood, B Warrell, D Tomkins, A Tugwell, P Zalin, A Bryceson, A Parry, E Brueton, M Duggan, M Rajković, A |
author_sort | Whittle, H |
collection | OXFORD |
description | In a controlled trial chloramphenicol proved as effective and much cheaper than penicillin for the treatment of group A meningococcal meningitis in Zaria, Nigeria. A short course of five days cured most patients. Adults and older children were soon able to take chloramphenicol by mouth, which reduced the cost and simplified treatment.It is suggested that chloramphenicol is a suitable alternative to sulphonamides for the treatment of meningococcal meningitis in those parts of Africa where the organism is sulphonamide-resistant. |
first_indexed | 2024-03-06T21:13:55Z |
format | Journal article |
id | oxford-uuid:3f1edc16-d1e7-43fc-b087-5e42f15bbd04 |
institution | University of Oxford |
language | English |
last_indexed | 2024-03-06T21:13:55Z |
publishDate | 1973 |
record_format | dspace |
spelling | oxford-uuid:3f1edc16-d1e7-43fc-b087-5e42f15bbd042022-03-26T14:29:56ZTrial of chloramphenicol for meningitis in northern savanna of Africa.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:3f1edc16-d1e7-43fc-b087-5e42f15bbd04EnglishSymplectic Elements at Oxford1973Whittle, HDavidson, NGreenwood, BWarrell, DTomkins, ATugwell, PZalin, ABryceson, AParry, EBrueton, MDuggan, MRajković, AIn a controlled trial chloramphenicol proved as effective and much cheaper than penicillin for the treatment of group A meningococcal meningitis in Zaria, Nigeria. A short course of five days cured most patients. Adults and older children were soon able to take chloramphenicol by mouth, which reduced the cost and simplified treatment.It is suggested that chloramphenicol is a suitable alternative to sulphonamides for the treatment of meningococcal meningitis in those parts of Africa where the organism is sulphonamide-resistant. |
spellingShingle | Whittle, H Davidson, N Greenwood, B Warrell, D Tomkins, A Tugwell, P Zalin, A Bryceson, A Parry, E Brueton, M Duggan, M Rajković, A Trial of chloramphenicol for meningitis in northern savanna of Africa. |
title | Trial of chloramphenicol for meningitis in northern savanna of Africa. |
title_full | Trial of chloramphenicol for meningitis in northern savanna of Africa. |
title_fullStr | Trial of chloramphenicol for meningitis in northern savanna of Africa. |
title_full_unstemmed | Trial of chloramphenicol for meningitis in northern savanna of Africa. |
title_short | Trial of chloramphenicol for meningitis in northern savanna of Africa. |
title_sort | trial of chloramphenicol for meningitis in northern savanna of africa |
work_keys_str_mv | AT whittleh trialofchloramphenicolformeningitisinnorthernsavannaofafrica AT davidsonn trialofchloramphenicolformeningitisinnorthernsavannaofafrica AT greenwoodb trialofchloramphenicolformeningitisinnorthernsavannaofafrica AT warrelld trialofchloramphenicolformeningitisinnorthernsavannaofafrica AT tomkinsa trialofchloramphenicolformeningitisinnorthernsavannaofafrica AT tugwellp trialofchloramphenicolformeningitisinnorthernsavannaofafrica AT zalina trialofchloramphenicolformeningitisinnorthernsavannaofafrica AT brycesona trialofchloramphenicolformeningitisinnorthernsavannaofafrica AT parrye trialofchloramphenicolformeningitisinnorthernsavannaofafrica AT bruetonm trialofchloramphenicolformeningitisinnorthernsavannaofafrica AT dugganm trialofchloramphenicolformeningitisinnorthernsavannaofafrica AT rajkovica trialofchloramphenicolformeningitisinnorthernsavannaofafrica |