Reporting recommendations for tumor marker prognostic studies (REMARK): explanation and elaboration.
BACKGROUND: The Reporting Recommendations for Tumor Marker Prognostic Studies (REMARK) checklist consists of 20 items to report for published tumor marker prognostic studies. It was developed to address widespread deficiencies in the reporting of such studies. In this paper we expand on the REMARK...
| Main Authors: | , , , |
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| Format: | Journal article |
| Language: | English |
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BioMed Central
2012
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| _version_ | 1797064418200125440 |
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| author | Altman, D McShane, L Sauerbrei, W Taube, SE |
| author_facet | Altman, D McShane, L Sauerbrei, W Taube, SE |
| author_sort | Altman, D |
| collection | OXFORD |
| description | BACKGROUND: The Reporting Recommendations for Tumor Marker Prognostic Studies (REMARK) checklist consists of 20 items to report for published tumor marker prognostic studies. It was developed to address widespread deficiencies in the reporting of such studies. In this paper we expand on the REMARK checklist to enhance its use and effectiveness through better understanding of the intent of each item and why the information is important to report. METHODS: REMARK recommends including a transparent and full description of research goals and hypotheses, subject selection, specimen and assay considerations, marker measurement methods, statistical design and analysis, and study results. Each checklist item is explained and accompanied by published examples of good reporting, and relevant empirical evidence of the quality of reporting. We give prominence to discussion of the 'REMARK profile', a suggested tabular format for summarizing key study details. SUMMARY: The paper provides a comprehensive overview to educate on good reporting and provide a valuable reference for the many issues to consider when designing, conducting, and analyzing tumor marker studies and prognostic studies in medicine in general. To encourage dissemination of the Reporting Recommendations for Tumor Marker Prognostic Studies (REMARK): Explanation and Elaboration, this article has also been published in PLoS Medicine. |
| first_indexed | 2024-03-06T21:14:00Z |
| format | Journal article |
| id | oxford-uuid:3f293131-313b-4dbe-befe-a50b48503855 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T21:14:00Z |
| publishDate | 2012 |
| publisher | BioMed Central |
| record_format | dspace |
| spelling | oxford-uuid:3f293131-313b-4dbe-befe-a50b485038552022-03-26T14:30:08ZReporting recommendations for tumor marker prognostic studies (REMARK): explanation and elaboration.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:3f293131-313b-4dbe-befe-a50b48503855EnglishSymplectic Elements at OxfordBioMed Central2012Altman, DMcShane, LSauerbrei, WTaube, SE BACKGROUND: The Reporting Recommendations for Tumor Marker Prognostic Studies (REMARK) checklist consists of 20 items to report for published tumor marker prognostic studies. It was developed to address widespread deficiencies in the reporting of such studies. In this paper we expand on the REMARK checklist to enhance its use and effectiveness through better understanding of the intent of each item and why the information is important to report. METHODS: REMARK recommends including a transparent and full description of research goals and hypotheses, subject selection, specimen and assay considerations, marker measurement methods, statistical design and analysis, and study results. Each checklist item is explained and accompanied by published examples of good reporting, and relevant empirical evidence of the quality of reporting. We give prominence to discussion of the 'REMARK profile', a suggested tabular format for summarizing key study details. SUMMARY: The paper provides a comprehensive overview to educate on good reporting and provide a valuable reference for the many issues to consider when designing, conducting, and analyzing tumor marker studies and prognostic studies in medicine in general. To encourage dissemination of the Reporting Recommendations for Tumor Marker Prognostic Studies (REMARK): Explanation and Elaboration, this article has also been published in PLoS Medicine. |
| spellingShingle | Altman, D McShane, L Sauerbrei, W Taube, SE Reporting recommendations for tumor marker prognostic studies (REMARK): explanation and elaboration. |
| title | Reporting recommendations for tumor marker prognostic studies (REMARK): explanation and elaboration. |
| title_full | Reporting recommendations for tumor marker prognostic studies (REMARK): explanation and elaboration. |
| title_fullStr | Reporting recommendations for tumor marker prognostic studies (REMARK): explanation and elaboration. |
| title_full_unstemmed | Reporting recommendations for tumor marker prognostic studies (REMARK): explanation and elaboration. |
| title_short | Reporting recommendations for tumor marker prognostic studies (REMARK): explanation and elaboration. |
| title_sort | reporting recommendations for tumor marker prognostic studies remark explanation and elaboration |
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