Identification of tuberculosis susceptibility genes with human macrophage gene expression profiles

Although host genetics influences susceptibility to tuberculosis (TB), few genes determining disease outcome have been identified. We hypothesized that macrophages from individuals with different clinical manifestations of Mycobacterium tuberculosis (Mtb) infection would have distinct gene expressio...

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Hlavní autoři: Thuong, N, Dunstan, S, Chau, T, Thorsson, V, Simmons, C, Quyen, N, Thwaites, G, Lan, N, Hibberd, M, Teo, Y, Seielstad, M, Aderem, A, Farrar, J, Hawn, T
Médium: Journal article
Jazyk:English
Vydáno: 2008