Genetics of colorectal cancer: hereditary aspects and overview of colorectal tumorigenesis.
Familial adenomatous polyposis and hereditary non-polyposis colorectal cancer are dominantly inherited conditions with 100% and 80% life-time risk of developing colorectal cancer, respectively. The genetic mutations responsible for these two conditions lie in the adenomatous polyposis coli (APC) and...
Main Authors: | Fearnhead, N, Wilding, J, Bodmer, W |
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Format: | Journal article |
Language: | English |
Published: |
2002
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