Arylamine N-Acetyltransferases from mycobacteria: investigations of a potential yarget for anti-tubercular therapy

Arylamine N-Acetyltransferases from mycobacteria: investigations of a potential yarget for anti-tubercular therapy

<p>Reactivation of latent infection is the major cause of tuberculosis (TB). Cholesterol is a critical carbon source during latent infection. Catabolism of cholesterol contributes to the pool of propionyl-CoA, a precursor that is incorporated into cell-wall lipids.</p> <p>Arylamine...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखक:	Abuhammad, A
अन्य लेखक:	Sim, E
स्वरूप:	थीसिस
भाषा:	English
प्रकाशित:	2013
विषय:	Pharmacology Medical sciences

समान संसाधन

Identification of arylamine N-acetyltransferase inhibitors as an approach towards novel anti-tuberculars.
द्वारा: Westwood, I, और अन्य
प्रकाशित: (2010)

Piperidinols that show anti-tubercular activity as inhibitors of arylamine N-acetyltransferase: an essential enzyme for mycobacterial survival inside macrophages
द्वारा: Abuhammad, A, और अन्य
प्रकाशित: (2012)

Investigating the endogenous role of human n-acetyltransferase 1, as potential breast cancer biomarker, using chemical biology
द्वारा: Laurieri, N
प्रकाशित: (2012)

Piperidinols that show anti-tubercular activity as inhibitors of arylamine N-acetyltransferase: an essential enzyme for mycobacterial survival inside macrophages.
द्वारा: Areej Abuhammad, और अन्य
प्रकाशित: (2012-01-01)

Structural Studies on the Mycobacterial Arylamine N-Acetyltransferases
द्वारा: Abuhammad, A, और अन्य
प्रकाशित: (2010)

The structure of arylamine N-acetyltransferase from Mycobacterium smegmatis--an enzyme which inactivates the anti-tubercular drug, isoniazid.
द्वारा: Sandy, J, और अन्य
प्रकाशित: (2002)

Analysis of β-amino alcohols as inhibitors of the potential anti-tubercular target N-acetyltransferase.
द्वारा: Fullam, E, और अन्य
प्रकाशित: (2011)

Comparison of the Arylamine N-acetyltransferase from Mycobacterium marinum and Mycobacterium tuberculosis.
द्वारा: Fullam, E, और अन्य
प्रकाशित: (2009)

Probing the architecture of the Mycobacterium marinum arylamine N-acetyltransferase active site.
द्वारा: Abuhammad, A, और अन्य
प्रकाशित: (2010)

Mapping the genes for arylamine N-acetyltransferases
द्वारा: Fakis, G
प्रकाशित: (2000)

Structure and mechanism of arylamine N-acetyltransferases.
द्वारा: Westwood, I, और अन्य
प्रकाशित: (2006)

Arylamine N-acetyltransferase in adult mouse brain
द्वारा: Mo, M, और अन्य
प्रकाशित: (2004)

Expression of the genes for arylamine N-acetyltransferases in mice
द्वारा: Boukouvala, S, और अन्य
प्रकाशित: (2002)

Structural investigation of mutant Mycobacterium smegmatis arylamine N-acetyltransferase: a model for a naturally occurring functional polymorphism in Mycobacterium tuberculosis arylamine N-acetyltransferase.
द्वारा: Kawamura, A, और अन्य
प्रकाशित: (2003)

Neuroendocrine expression of mouse arylamine N-acetyltransferase 2
द्वारा: Wakefield, L, और अन्य
प्रकाशित: (2006)

Arylamine N-acetyltransferases: structural and functional implications of polymorphisms.
द्वारा: Sim, E, और अन्य
प्रकाशित: (2008)

Selective small molecule inhibitors of the potential breast cancer marker, human arylamine N-acetyltransferase 1, and its murine homologue, mouse arylamine N-acetyltransferase 2.
द्वारा: Russell, A, और अन्य
प्रकाशित: (2009)

Differences between murine arylamine N-acetyltransferase type 1 and human arylamine N-acetyltransferase type 2 defined by substrate specificity and inhibitor binding
द्वारा: Laurieri, N, और अन्य
प्रकाशित: (2014)

Eukaryotic arylamine N-acetyltransferase. Investigation of substrate specificity by high-throughput screening.
द्वारा: Kawamura, A, और अन्य
प्रकाशित: (2005)

An approach to identifying novel substrates of bacterial arylamine N-acetyltransferases.
द्वारा: Brooke, E, और अन्य
प्रकाशित: (2003)

Arylamine N-acetyltransferase expression during murine heart development
द्वारा: Wakefield, L, और अन्य
प्रकाशित: (2004)

Arylamine N-acetyltransferase 2 gene polymorphism in an Algerian population
द्वारा: Hiba Chelouti, और अन्य
प्रकाशित: (2017-08-01)

Biochemical Characterization of Arylamine N-acetyltransferases From Vibrio vulnificus
द्वारा: Xinning Liu, और अन्य
प्रकाशित: (2021-01-01)

Inhibition of mycobacterial arylamine N-acetyltransferase contributes to anti-mycobacterial activity of Warburgia salutaris.
द्वारा: Madikane, V, और अन्य
प्रकाशित: (2007)

Inhibition of mycobacterial arylamine N-acetyltransferase contributes to anti-mycobacterial activity of Warburgia salutaris
द्वारा: Madikane, V, और अन्य
प्रकाशित: (2007)

Protein-ligand interactions of arylamine N-acetyltransferase from Mycobacterium smegmatis
द्वारा: Brooke, E
प्रकाशित: (2003)

Polymorphisms of arylamine N-acetyltransferase2 and risk of lung and colorectal cancer
द्वारा: Amjad Mahasneh, और अन्य
प्रकाशित: (2012-01-01)

Arylamine N-Acetyltransferase 1 Activity is Regulated by the Protein Acetylation Status
द्वारा: Raúl A. Salazar-González, और अन्य
प्रकाशित: (2022-01-01)

Hamster arylamine N-acetyltransferase 2: Investigation of substrate specificity by high-through-put screening
द्वारा: Kawamura, A, और अन्य
प्रकाशित: (2004)

Over-expression, purification, and characterization of recombinant human arylamine N-acetyltransferase 1.
द्वारा: Wang, H, और अन्य
प्रकाशित: (2005)

Distribution of arylamine N-acetyltransferase 2 (NAT2) genotypes among Omanis
द्वारा: Musbah O. M. Tanira, और अन्य
प्रकाशित: (2003-04-01)

Humans and Chimpanzees Display Opposite Patterns of Diversity in Arylamine N-Acetyltransferase Genes
द्वारा: Christelle Vangenot, और अन्य
प्रकाशित: (2019-07-01)

Arylamine N-acetyltransferase 2 genotype-dependent N-acetylation of isoniazid in cryopreserved human hepatocytes
द्वारा: Mark A. Doll, और अन्य
प्रकाशित: (2017-07-01)

Characterization of the putative operon containing arylamine N-acetyltransferase (nat) in Mycobacterium bovis BCG.
द्वारा: Anderton, M, और अन्य
प्रकाशित: (2006)

Characterization of the putative operon containing arylamine N−acetyltransferase (nat) in Mycobacterium bovis BCG
द्वारा: Eltis, E
प्रकाशित: (2006)

Structure of arylamine N-acetyltransferase from Mycobacterium tuberculosis determined by cross-seeding with the homologous protein from M. marinum: triumph over adversity.
द्वारा: Abuhammad, A, और अन्य
प्रकाशित: (2013)

Pathogenic mycobacteria achieve cellular persistence via lipid-mediated inhibition of the Niemann-Pick disease type C pathway
द्वारा: Fineran, PD
प्रकाशित: (2014)

Network pharmacology and in silico investigation into the therapeutic potential of phytoconstituents of Peucedanum ostruthium as anti-tubercular agents
द्वारा: Neeru Bhanwala, और अन्य
प्रकाशित: (2025-03-01)

Synthesis and in vitro evaluation of novel small molecule inhibitors of bacterial arylamine N-acetyltransferases (NATs).
द्वारा: Brooke, E, और अन्य
प्रकाशित: (2003)

Novel small-molecule inhibitors of arylamine N-acetyltransferases: drug discovery by high-throughput screening.
द्वारा: Westwood, I, और अन्य
प्रकाशित: (2011)