Rapid desensitisation of the GH secretagogue (ghrelin) receptor to hexarelin in vitro.

Ghrelin, the recently identified hormone with GH-secreting and appetite-inducing effects, acts on the GH secretagogue receptor (GHS-R). GHS-R belongs to the G protein-coupled 7 transmembrane domain receptors and activates the phospholipase C pathway; it then leads to the release of GH from somatotro...

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Hlavní autoři: Orkin, R, New, D, Norman, D, Chew, S, Clark, A, Grossman, AB, Korbonits, M
Médium: Journal article
Jazyk:English
Vydáno: 2003

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