Rapid desensitisation of the GH secretagogue (ghrelin) receptor to hexarelin in vitro.
Ghrelin, the recently identified hormone with GH-secreting and appetite-inducing effects, acts on the GH secretagogue receptor (GHS-R). GHS-R belongs to the G protein-coupled 7 transmembrane domain receptors and activates the phospholipase C pathway; it then leads to the release of GH from somatotro...
Những tác giả chính: | Orkin, R, New, D, Norman, D, Chew, S, Clark, A, Grossman, AB, Korbonits, M |
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Định dạng: | Journal article |
Ngôn ngữ: | English |
Được phát hành: |
2003
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