Development of macrocycle kinase inhibitors for ALK2 using Fibrodysplasia ossificans progressiva‐derived endothelial cells
<p style="text-align:justify;"> Fibrodysplasia ossificans progressiva (FOP) is an extremely rare congenital form of heterotopic ossification (HO), caused by heterozygous mutations in the Activin A type I receptor (ACVR1), that encodes the bone morphogenetic protein (BMP) type I rece...
Main Authors: | Sánchez‐Duffhues, G, Williams, E, Benderitter, P, Kerr, G, Bullock, A |
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Format: | Journal article |
Published: |
Wiley
2019
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