IAPs: from caspase inhibitors to modulators of NF-kappaB, inflammation and cancer.
The realization that alterations in inhibitor of apoptosis (IAP) proteins are found in many types of human cancer and are associated with chemoresistance, disease progression and poor prognosis, has sparked a worldwide frenzy in the development of small pharmacological inhibitors of IAPs. The develo...
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2010
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