Native tandem and ion mobility mass spectrometry highlight structural and modular similarities in clustered-regularly-interspaced shot-palindromic-repeats (CRISPR)-associated protein complexes from Escherichia coli and Pseudomonas aeruginosa.

Native tandem and ion mobility mass spectrometry highlight structural and modular similarities in clustered-regularly-interspaced shot-palindromic-repeats (CRISPR)-associated protein complexes from Escherichia coli and Pseudomonas aeruginosa.

The CRISPR/Cas (clustered regularly interspaced short palindromic repeats/CRISPR-associated genes) immune system of bacteria and archaea provides acquired resistance against viruses and plasmids, by a strategy analogous to RNA-interference. Key components of the defense system are ribonucleoprotein...

Full description

Bibliographic Details
Main Authors: van Duijn, E, Barbu, I, Barendregt, A, Jore, M, Wiedenheft, B, Lundgren, M, Westra, E, Brouns, S, Doudna, J, van der Oost, J, Heck, A
Format: Journal article
Language:English
Published: 2012

Similar Items