Copper-mediated nucleophilic 18F-radiolabelling of (hetero)arenes for applications in positron emission tomography

This thesis focuses on the development of a novel nucleophilic 18F-fluorination of (hetero)arenes and of a rapid screening experiment to facilitate the application of this reaction to complex heterocyclic targets of medicinal importance. <strong&...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awdur:	Taylor, N
Awduron Eraill:	Gouverneur, V
Fformat:	Traethawd Ymchwil
Iaith:	English
Cyhoeddwyd:	2017
Pynciau:	Tomography, Emission Fluorination

Eitemau Tebyg

Reaction of [18F]Fluoride at Heteroatoms and Metals for Imaging of Peptides and Proteins by Positron Emission Tomography
gan: Kymberley R. Scroggie, et al.
Cyhoeddwyd: (2021-06-01)

Novel methods for 18F-radiolabelling
gan: Calderwood, S
Cyhoeddwyd: (2016)

Fluorine-18 fluorodeoxyglucose positron emission tomography for cardiac sarcoidosis—is it time to consider a new radiotracer?
gan: Georgios Christopoulos, et al.
Cyhoeddwyd: (2017-08-01)

Prevalence of cancer and the benign call rate of afirma gene classifier in 18F‐Fluorodeoxyglucose positron emission tomography positive cytologically indeterminate thyroid nodules
gan: Mayumi Endo, et al.
Cyhoeddwyd: (2021-02-01)

The diagnostic yield of fluorine-18 fluorodeoxyglucose positron emission tomography-computed tomography in recurrent testicular seminoma
gan: Athanasios Bantis, et al.
Cyhoeddwyd: (2016-01-01)

Comparison of pathological findings and accumulation of fluorin-18 fluorodeoxyglucose on positron emission tomography/computed tomography: A case of relapsing polychondritis
gan: Hirokazu Tokuyasu, et al.
Cyhoeddwyd: (2023-01-01)

Pyrazoles as Key Scaffolds for the Development of Fluorine-18-Labeled Radiotracers for Positron Emission Tomography (PET)
gan: Pedro M. O. Gomes, et al.
Cyhoeddwyd: (2020-04-01)

Radiolabelled Peptides for Positron Emission Tomography and Endoradiotherapy in Oncology
gan: Christine Rangger, et al.
Cyhoeddwyd: (2020-01-01)

Carbon-11 and Fluorine-18 Labeled Amino Acid Tracers for Positron Emission Tomography Imaging of Tumors
gan: Aixia Sun, et al.
Cyhoeddwyd: (2018-01-01)

Radiosynthesis and Early Evaluation of a Positron Emission Tomography Imaging Probe [18F]AGAL Targeting Alpha-Galactosidase A Enzyme for Fabry Disease
gan: Talakad G. Lohith, et al.
Cyhoeddwyd: (2023-10-01)

Positron emission tomography and positron emission tomography-computerized tomography in pediatric patients
gan: Patel Chetan, et al.
Cyhoeddwyd: (2007-01-01)

Quantification of Skeletal Muscle Perfusion in Peripheral Artery Disease Using 18F‐Sodium Fluoride Positron Emission Tomography Imaging
gan: Ting‐Heng Chou, et al.
Cyhoeddwyd: (2024-02-01)

Intraosseous malignant peripheral nerve sheath tumor of distal femur detected with fluorine-18 fluorodeoxyglucose positron emission tomography/computed tomography imaging
gan: Koramadai Karuppusamy Kamaleshwaran, et al.
Cyhoeddwyd: (2016-01-01)

The Radiolabeling of a Gly-Sar Dipeptide Derivative with Flourine-18 and Its Use as a Potential Peptide Transporter PET Imaging Agent
gan: Andrei Molotkov, et al.
Cyhoeddwyd: (2020-02-01)

The 18F-fluorodeoxyglucose positron emission tomography/computed tomography in breast cancer
gan: Mihailović Jasna, et al.
Cyhoeddwyd: (2017-01-01)

An Assessment of Early Response to Targeted Therapy via Molecular Imaging: A Pilot Study of 3′-deoxy-3′[(18)F]-Fluorothymidine Positron Emission Tomography 18F-FLT PET/CT in Prostate Adenocarcinoma
gan: Kalevi Kairemo, et al.
Cyhoeddwyd: (2017-04-01)

F-18 fluorodeoxyglucose positron emission tomography/computed tomography in the infection of heart
gan: Eunjung Kong
Cyhoeddwyd: (2021-04-01)

Closing the gap between 19F and 18F chemistry
gan: Javier Ajenjo, et al.
Cyhoeddwyd: (2021-09-01)

Pleural mesothelioma with peritoneal involvement: Diagnosed on 18F-FDG positron emission tomography/computed tomography
gan: Anuja Anand, et al.
Cyhoeddwyd: (2019-01-01)

Rare case of isolated adrenal metastasis from hepatocellular carcinoma without intrahepatic recurrence after hepatic resection detected with fluorine-18 fluorodeoxyglucose-positron emission tomography/computed tomography
gan: Koramadai Karuppusamy Kamaleshwaran, et al.
Cyhoeddwyd: (2015-01-01)

Development of a highly-specific 18F-labeled irreversible positron emission tomography tracer for monoacylglycerol lipase mapping
gan: Zhen Chen, et al.
Cyhoeddwyd: (2021-06-01)

(18)F‐fluorodeoxyglucose uptake by positron emission tomography in patients with IPAH and CTEPH
gan: Celik Sumer, et al.
Cyhoeddwyd: (2024-04-01)

Silicon-[18F]Fluorine Radiochemistry: Basics, Applications and Challenges
gan: Carmen Wängler, et al.
Cyhoeddwyd: (2012-03-01)

18F-FLOURODEOXYGLUCOSE (18FDG) POSITRON-EMISSION TOMOGRAPHY (PET) AS IMAGING MODALITIES ON THYROID CANCER MANAGEMENT
gan: I Putu Ary Wismayana, et al.
Cyhoeddwyd: (2013-07-01)

Diagnostic Role of F-18 Fluorodeoxyglucose Positron-Emission Tomography/Computed Tomography in Restaging of Upper Urinary Tract Urothelial Carcinoma
gan: Hakan Öztürk
Cyhoeddwyd: (2017-09-01)

Frequency of skeletal metastasis on 18F-fluorodeoxyglucose positron emission tomography/computed tomography with negative computed tomography at Institute of Nuclear Medicine and Oncology
gan: Mariam Fayyaz, et al.
Cyhoeddwyd: (2022-11-01)

Novel radiochemistry for positron emission tomography imaging
gan: Tack, O
Cyhoeddwyd: (2020)

An overview of 18F-fluorodeoxyglucose positron emission tomography/computed tomography in giant cell arteritis
gan: Thomas Thibault, et al.
Cyhoeddwyd: (2024-10-01)

Localization of focus by 18 F-fludeoxyglucose positron emission tomography computed tomography in the definitive diagnosis of infective endocarditis
gan: Sathyamurthy Immaneni, et al.
Cyhoeddwyd: (2020-01-01)

Embryo/Fetus doses from 18F-fludeoxyglucose radiopharmaceutical in positron emission tomography/computed tomography
gan: Nazenin Ipek Isikci, et al.
Cyhoeddwyd: (2022-01-01)

The emerging role of whole-body 18F-fluorodeoxyglucose positron emission tomography in patients with sarcoidosis
gan: Silvia Taralli, et al.
Cyhoeddwyd: (2012-01-01)

Synthesis of 18fluoride-fluorodeoxyglucose and its clinical applications in positron emission tomography/computed tomography
gan: Rajeev Kumar, et al.
Cyhoeddwyd: (2022-09-01)

Evaluation of the Performance of 18F-Fluorothymidine Positron Emission Tomography/Computed Tomography (18F-FLT-PET/CT) in Metastatic Brain Lesions
gan: Alexandra Nikaki, et al.
Cyhoeddwyd: (2019-01-01)

Assessment of Using 18F-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography in Patients with Carcinoma of Unknown Primary
gan: S. A. Yaremenko, et al.
Cyhoeddwyd: (2021-09-01)

18F-fluorodeoxyglucose positron emission tomography and magnetic resonance imaging evaluation of chorea
gan: Nobuyuki Ishii, et al.
Cyhoeddwyd: (2018-09-01)

Recurrent Proliferating Trichilemmal Tumor with Malignant Change on the F-18 Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography
gan: Eun Ha Moon, et al.
Cyhoeddwyd: (2016-06-01)

Comparison of 18F-fluorothymidine Positron Emission Tomography/Computed Tomography and 18F-fluorodeoxyglucose Positron Emission Tomography/Computed Tomography in Patients with Breast Cancer
gan: Mio Mori, et al.
Cyhoeddwyd: (2022-10-01)

Intratumoral Injection of Anlotinib Hydrogel Combined With Radiotherapy Reduces Hypoxia in Lewis Lung Carcinoma Xenografts: Assessment by Micro Fluorine-18-fluoromisonidazole Positron Emission Tomography/Computed Tomography Hypoxia Imaging
gan: Qin Gao, et al.
Cyhoeddwyd: (2021-03-01)

Exploring Alternative Radiolabeling Strategies for Sialic Acid-Binding Immunoglobulin-Like Lectin 9 Peptide: [68Ga]Ga- and [18F]AlF-NOTA-Siglec-9
gan: Olli Moisio, et al.
Cyhoeddwyd: (2018-01-01)

Advances in [18F]Trifluoromethylation Chemistry for PET Imaging
gan: Felix Francis, et al.
Cyhoeddwyd: (2021-10-01)