Investigating mechanisms of TDP-43 toxicity in cellular models of amyotrophic lateral sclerosis

Amyotrophic lateral sclerosis (ALS) is a fatal, neurodegenerative disorder for which there is currently no cure. TDP-43 cytoplasmic mislocalisation and aggregation are the pathological hallmarks of the disease, and mutations in the gene encoding TDP-43, TARDBP, have been observed in a small number o...

Cur síos iomlán

Sonraí bibleagrafaíochta
Príomhchruthaitheoir: Carroll, E
Rannpháirtithe: Talbot, K
Formáid: Tráchtas
Teanga:English
Foilsithe / Cruthaithe: 2022
Ábhair: