Investigating mechanisms of TDP-43 toxicity in cellular models of amyotrophic lateral sclerosis

Amyotrophic lateral sclerosis (ALS) is a fatal, neurodegenerative disorder for which there is currently no cure. TDP-43 cytoplasmic mislocalisation and aggregation are the pathological hallmarks of the disease, and mutations in the gene encoding TDP-43, TARDBP, have been observed in a small number o...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй
Үндсэн зохиолч: Carroll, E
Бусад зохиолчид: Talbot, K
Формат: Дипломын ажил
Хэл сонгох:English
Хэвлэсэн: 2022
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