Investigating mechanisms of TDP-43 toxicity in cellular models of amyotrophic lateral sclerosis

Amyotrophic lateral sclerosis (ALS) is a fatal, neurodegenerative disorder for which there is currently no cure. TDP-43 cytoplasmic mislocalisation and aggregation are the pathological hallmarks of the disease, and mutations in the gene encoding TDP-43, TARDBP, have been observed in a small number o...

Olles dieđut

Bibliográfalaš dieđut
Váldodahkki: Carroll, E
Eará dahkkit: Talbot, K
Materiálatiipa: Oahppočájánas
Giella:English
Almmustuhtton: 2022
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