A common LPA null allele associates with lower lipoprotein(a) levels and coronary artery disease risk

OBJECTIVE - Increased levels of lipoprotein(a) are a highly heritable risk factor for coronary artery disease (CAD). The genetic determinants of lipoprotein(a) levels are mainly because of genetic variation in the apolipoprotein(a) gene (LPA). We have tested the association of a relatively common nu...

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Những tác giả chính: Kyriakou, T, Seedorf, U, Goel, A, Hopewell, J, Clarke, R, Watkins, H, Farrall, M
Định dạng: Journal article
Ngôn ngữ:English
Được phát hành: Lippincott Williams and Wilkins 2014