GTP cyclohydrolase II structure and mechanism.

GTP cyclohydrolase II structure and mechanism.

GTP cyclohydrolase II converts GTP to 2,5-diamino-6-beta-ribosyl-4(3H)-pyrimidinone 5'-phosphate, formate and pyrophosphate, the first step in riboflavin biosynthesis. The essential role of riboflavin in metabolism and the absence of GTP cyclohydrolase II in higher eukaryotes makes it a potenti...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون:	Ren, J, Kotaka, M, Lockyer, M, Lamb, H, Hawkins, A, Stammers, D
التنسيق:	Journal article
اللغة:	English
منشور في:	2005

مواد مشابهة

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Parkinson's disease in GTP cyclohydrolase 1 mutation carriers.
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Structures of R- and T-state Escherichia coli aspartokinase III. Mechanisms of the allosteric transition and inhibition by lysine.
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Control of GTP Cyclohydrolase I Activity during Aggregation of Dictyostelium discoideum
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GTP cyclohydrolase drives breast cancer development and promotes EMT in an enzyme-independent manner
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Regulation of β-adrenergic control of heart rate by GTP-cyclohydrolase 1 (GCH1) and tetrahydrobiopterin.
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Endothelial GTP cyclohydrolase and tetrahydrobiopterin regulate gestational blood pressure, uteroplacental remodeling and fetal growth
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Cardiomyocyte GTP cyclohydrolase 1 and tetrahydrobiopterin increase NOS1 activity and accelerate myocardial relaxation
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Overexpression of GTP cyclohydrolase 1 feedback regulatory protein is protective in a murine model of septic shock.
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Non-covalent interaction between polyubiquitin and GTP cyclohydrolase 1 dictates its degradation.
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Endothelial-targeted GTP cyclohydrolase I overexpression prevents blood pressure progression in mineralocorticoid hypertension
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Endothelial-targeted GTP cyclohydrolase I overexpression prevents blood pressure progression in mineralocorticoid hypertension\
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303A cell-Autonomous role for endothelial GTP cyclohydrolase 1 and tetrahydrobiopterin in blood pressure regulation.
حسب: Chuaiphichai, S, وآخرون
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Endotoxemia-related acute kidney injury in transgenic mice with endothelial overexpression of GTP cyclohydrolase-1.
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Influence of an Aromatic Amino Acid Decarboxylase Inhibitor on GTP Cyclohydrolase I Activity in the Rat Brain
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Genomic Organization of Mouse and Human GTP Cyclohydrolase I Genes and Mutations Found in the Human Gene
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Endothelium-targeted transgenic GTP-cyclohydrolase I overexpression inhibits neointima formation in mouse carotid artery.
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Endothelial-specific GTP cyclohydrolase I overexpression prevents blood pressure progression in salt-sensitive hypertension
حسب: Chen, A, وآخرون
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Cardiomyocyte-targeted overexpression of GTP cyclohydrolase-1 increases nNOS activity and hastens myocardial relaxation
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GTP cyclohydrolase I and tyrosine hydroxylase gene mutations in familial and sporadic dopa-responsive dystonia patients.
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Co-ordinate Expression of GTP Cyclohydrolase I and Inducible Nitric Oxide Synthase in Rat Mesangial Cells
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Cardiac myocyte-specific overexpression of human GTP cyclohydrolase I protects against acute cardiac allograft rejection.
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Endothelium-targeted GTP cyclohydrolase I overexpression inhibits wire injury-induced restenosis in mouse carotid artery
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Genetic variation in GCH1, encoding GTP-cyclohydrolase 1, regulates biopterin levels and endothelial function in atherosclerosis
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PRESERVATION OF ENDOTHELIAL GTP CYCLOHYDROLASE I ACTIVITY AND IMPROVEMENT OF RENAL NITRIC OXIDE AVAILABILITY PREVENT THE DEVELOPMENT OF DIABETIC NEPHROPATHY
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