GTP cyclohydrolase II structure and mechanism.

GTP cyclohydrolase II structure and mechanism.

GTP cyclohydrolase II converts GTP to 2,5-diamino-6-beta-ribosyl-4(3H)-pyrimidinone 5'-phosphate, formate and pyrophosphate, the first step in riboflavin biosynthesis. The essential role of riboflavin in metabolism and the absence of GTP cyclohydrolase II in higher eukaryotes makes it a potenti...

Полное описание

Библиографические подробности
Главные авторы:	Ren, J, Kotaka, M, Lockyer, M, Lamb, H, Hawkins, A, Stammers, D
Формат:	Journal article
Язык:	English
Опубликовано:	2005

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