GTP cyclohydrolase II structure and mechanism.
GTP cyclohydrolase II converts GTP to 2,5-diamino-6-beta-ribosyl-4(3H)-pyrimidinone 5'-phosphate, formate and pyrophosphate, the first step in riboflavin biosynthesis. The essential role of riboflavin in metabolism and the absence of GTP cyclohydrolase II in higher eukaryotes makes it a potenti...
Hlavní autoři: | , , , , , |
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Médium: | Journal article |
Jazyk: | English |
Vydáno: |
2005
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