Adjusting the effect of nonstationarity in cluster-based and TFCE inference.

In nonstationary images, cluster inference depends on the local image smoothness, as clusters tend to be larger in smoother regions by chance alone. In order to correct the inference for such nonstationary, cluster sizes can be adjusted according to a local smoothness estimate. In this study, adjust...

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Main Authors: Salimi-Khorshidi, G, Smith, S, Nichols, T
Format: Journal article
Language:English
Published: 2011
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author Salimi-Khorshidi, G
Smith, S
Nichols, T
author_facet Salimi-Khorshidi, G
Smith, S
Nichols, T
author_sort Salimi-Khorshidi, G
collection OXFORD
description In nonstationary images, cluster inference depends on the local image smoothness, as clusters tend to be larger in smoother regions by chance alone. In order to correct the inference for such nonstationary, cluster sizes can be adjusted according to a local smoothness estimate. In this study, adjusted cluster sizes are used in a permutation-testing framework for both cluster-based and threshold-free cluster enhancement (TFCE) inference and tested on both simulated and real data. We find that TFCE inference is already fairly robust to nonstationarity in the data, while cluster-based inference requires an adjustment to ensure homogeneity. A group of possible multi-level adjustments are introduced and their results on simulated and real data are assessed using a new performance index. We also find that adjusting for local smoothness via a separate resampling procedure is more effective at removing nonstationarity than an adjustment via a random field theory based smoothness estimator.
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spelling oxford-uuid:3fd5beaf-1527-4855-b079-3e02b7c5094e2022-03-26T14:34:27ZAdjusting the effect of nonstationarity in cluster-based and TFCE inference.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:3fd5beaf-1527-4855-b079-3e02b7c5094eEnglishSymplectic Elements at Oxford2011Salimi-Khorshidi, GSmith, SNichols, TIn nonstationary images, cluster inference depends on the local image smoothness, as clusters tend to be larger in smoother regions by chance alone. In order to correct the inference for such nonstationary, cluster sizes can be adjusted according to a local smoothness estimate. In this study, adjusted cluster sizes are used in a permutation-testing framework for both cluster-based and threshold-free cluster enhancement (TFCE) inference and tested on both simulated and real data. We find that TFCE inference is already fairly robust to nonstationarity in the data, while cluster-based inference requires an adjustment to ensure homogeneity. A group of possible multi-level adjustments are introduced and their results on simulated and real data are assessed using a new performance index. We also find that adjusting for local smoothness via a separate resampling procedure is more effective at removing nonstationarity than an adjustment via a random field theory based smoothness estimator.
spellingShingle Salimi-Khorshidi, G
Smith, S
Nichols, T
Adjusting the effect of nonstationarity in cluster-based and TFCE inference.
title Adjusting the effect of nonstationarity in cluster-based and TFCE inference.
title_full Adjusting the effect of nonstationarity in cluster-based and TFCE inference.
title_fullStr Adjusting the effect of nonstationarity in cluster-based and TFCE inference.
title_full_unstemmed Adjusting the effect of nonstationarity in cluster-based and TFCE inference.
title_short Adjusting the effect of nonstationarity in cluster-based and TFCE inference.
title_sort adjusting the effect of nonstationarity in cluster based and tfce inference
work_keys_str_mv AT salimikhorshidig adjustingtheeffectofnonstationarityinclusterbasedandtfceinference
AT smiths adjustingtheeffectofnonstationarityinclusterbasedandtfceinference
AT nicholst adjustingtheeffectofnonstationarityinclusterbasedandtfceinference