The Lgr5 intestinal stem cell signature: robust expression of proposed quiescent '+4' cell markers.

Two types of stem cells are currently defined in small intestinal crypts: cycling crypt base columnar (CBC) cells and quiescent '+4' cells. Here, we combine transcriptomics with proteomics to define a definitive molecular signature for Lgr5(+) CBC cells. Transcriptional profiling of FACS-s...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Muñoz, J, Stange, D, Schepers, A, van de Wetering, M, Koo, B, Itzkovitz, S, Volckmann, R, Kung, K, Koster, J, Radulescu, S, Myant, K, Versteeg, R, Sansom, O, van Es, J, Barker, N, van Oudenaarden, A, Mohammed, S, Heck, A, Clevers, H
Формат: Journal article
Хэл сонгох:English
Хэвлэсэн: 2012