The Lgr5 intestinal stem cell signature: robust expression of proposed quiescent '+4' cell markers.

Two types of stem cells are currently defined in small intestinal crypts: cycling crypt base columnar (CBC) cells and quiescent '+4' cells. Here, we combine transcriptomics with proteomics to define a definitive molecular signature for Lgr5(+) CBC cells. Transcriptional profiling of FACS-s...

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التفاصيل البيبلوغرافية
المؤلفون الرئيسيون:	Muñoz, J, Stange, D, Schepers, A, van de Wetering, M, Koo, B, Itzkovitz, S, Volckmann, R, Kung, K, Koster, J, Radulescu, S, Myant, K, Versteeg, R, Sansom, O, van Es, J, Barker, N, van Oudenaarden, A, Mohammed, S, Heck, A, Clevers, H
التنسيق:	Journal article
اللغة:	English
منشور في:	2012

The Lgr5 intestinal stem cell signature: robust expression of proposed quiescent '+4' cell markers.

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