The Lgr5 intestinal stem cell signature: robust expression of proposed quiescent '+4' cell markers.

Two types of stem cells are currently defined in small intestinal crypts: cycling crypt base columnar (CBC) cells and quiescent '+4' cells. Here, we combine transcriptomics with proteomics to define a definitive molecular signature for Lgr5(+) CBC cells. Transcriptional profiling of FACS-s...

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Detaylı Bibliyografya
Asıl Yazarlar:	Muñoz, J, Stange, D, Schepers, A, van de Wetering, M, Koo, B, Itzkovitz, S, Volckmann, R, Kung, K, Koster, J, Radulescu, S, Myant, K, Versteeg, R, Sansom, O, van Es, J, Barker, N, van Oudenaarden, A, Mohammed, S, Heck, A, Clevers, H
Materyal Türü:	Journal article
Dil:	English
Baskı/Yayın Bilgisi:	2012

The Lgr5 intestinal stem cell signature: robust expression of proposed quiescent '+4' cell markers.

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