Hypertrophic and dilated cardiomyopathycausing mutations of troponin and alpha-tropomyosin have opposite effects on thin filament calcium binding

Geahča maid

• Dilated and hypertrophic cardiomyopathy mutations in troponin and alpha-tropomyosin have opposing effects on the calcium affinity of cardiac thin filaments.
  Dahkki: Robinson, P, et al.
  Almmustuhtton: (2007)
• Using fluorescence emission spectroscopy to asses the Ca2+ affinity of reconstituted troponin and thin filaments containing cardiomyopathy causing mutations of troponin and alpha-tropomyosin
  Dahkki: Robinson, P, et al.
  Almmustuhtton: (2007)
• Functional effects of mutations in troponin T and tropomyosin which cause dilated cardiomyopathy
  Dahkki: Robinson, P, et al.
  Almmustuhtton: (2003)
• Mutations in fast skeletal troponin I, troponin T and beta-tropomyosin that cause distal arthrogryposis all enhance thin filament activation
  Dahkki: Robinson, P, et al.
  Almmustuhtton: (2005)
• Dilated cardiomyopathy causing mutations in cardiac troponin T (TNT), cardiac troponin C (TNC), and alpha tropomyosin (TM) reduce CA(2+) sensitivity and maximum calcium activation
  Dahkki: Redwood, C, et al.
  Almmustuhtton: (2004)