Endothelin is a downstream mediator of profibrotic responses to transforming growth factor beta in human lung fibroblasts.

Endothelin is a downstream mediator of profibrotic responses to transforming growth factor beta in human lung fibroblasts.

OBJECTIVE: Fibrosis is excessive scarring caused by the accumulation and contraction of extracellular matrix proteins and is a common end pathway in many chronic diseases, including scleroderma (systemic sclerosis [SSc]). Indeed, pulmonary fibrosis is a major cause of death in SSc. Transforming gro...

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Bibliografische gegevens
Hoofdauteurs:	Shi-wen, X, Kennedy, L, Renzoni, E, Bou-Gharios, G, du Bois, R, Black, C, Denton, C, Abraham, D, Leask, A
Formaat:	Journal article
Taal:	English
Gepubliceerd in:	2007

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