Endothelin is a downstream mediator of profibrotic responses to transforming growth factor beta in human lung fibroblasts.
OBJECTIVE: Fibrosis is excessive scarring caused by the accumulation and contraction of extracellular matrix proteins and is a common end pathway in many chronic diseases, including scleroderma (systemic sclerosis [SSc]). Indeed, pulmonary fibrosis is a major cause of death in SSc. Transforming gro...
मुख्य लेखकों: | , , , , , , , , |
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स्वरूप: | Journal article |
भाषा: | English |
प्रकाशित: |
2007
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