Variable regions of antibodies and T-cell receptors may not be sufficient in molecular simulations investigating binding.
Antibodies and T-cell receptors are important proteins of the immune system that share similar structures. Both contain variable and constant regions. Insight into the dynamics of their binding can be provided by computational simulations. For these simulations the constant regions are often removed...
Main Authors: | Knapp, B, Dunbar, J, Alcala, M, Deane, C |
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Format: | Journal article |
Language: | English |
Published: |
American Chemical Society
2017
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