Photoaffinity labelling of isopenicillin N synthetase.

Photoaffinity labelling of isopenicillin N synthetase.

The alpha-aminoadipoyl group of the natural substrate of isopenicillin N synthetase (IPNS), L-alpha-aminoadipoyl-L-cysteinyl-D-valine (ACV), has been replaced by a diazirinyl-containing group, which can be photoactivated. This has allowed investigation of the substrate binding site of IPNS by photoa...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों:	Baldwin, J, Coates, J, Moloney, M, Pratt, A, Willis, A
स्वरूप:	Journal article
भाषा:	English
प्रकाशित:	1990

समान संसाधन

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Base-Mediated One-Pot Synthesis of Aliphatic Diazirines for Photoaffinity Labeling
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