Controlling the substrate selectivity of deacetoxycephalosporin/deacetylcephalosporin C synthase.

Deacetoxycephalosporin/deacetylcephalosporin C synthase (DAOC/DACS) is an iron(II) and 2-oxoglutarate-dependent oxygenase involved in the biosynthesis of cephalosporin C in Cephalosporium acremonium. It catalyzes two oxidative reactions, oxidative ring-expansion of penicillin N to deacetoxycephalosp...

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Hlavní autoři: Lloyd, MD, Lipscomb, S, Hewitson, K, Hensgens, C, Baldwin, J, Schofield, C
Médium: Journal article
Jazyk:English
Vydáno: 2004