An algorithm to detect chimeric clones and random noise in genomic mapping.
Experimental noise and noncontiguous clone inserts can pose serious problems in reconstructing genomic maps from hybridization data. We describe an algorithm that easily identifies false positive signals and clones containing chimeric inserts/internal deletions. The algorithm "dechimerizes"...
Main Authors: | Grigoriev, A, Mott, R, Lehrach, H |
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Format: | Journal article |
Language: | English |
Published: |
1994
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