The ATP- and tolbutamide-sensitivity of the ATP-sensitive K-channel from human pancreatic B cells.

The ATP- and sulphonylurea-sensitivity of the ATP-sensitive K-channel was measured in human pancreatic B cells. In inside-out patches, half-maximal inhibition of channel activity was produced by 10 mumol/l ATP (with 2 mM Mg2+) and ATP-inhibition was partially antagonised by ADP. A significantly lowe...

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Үндсэн зохиолчид: Ashcroft, F, Kakei, M, Gibson, J, Gray, D, Sutton, R
Формат: Journal article
Хэл сонгох:English
Хэвлэсэн: Springer-Verlag 1989

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