Degradation of interleukin 1beta by matrix metalloproteinases.

Degradation of interleukin 1beta by matrix metalloproteinases.

Matrix metalloproteinases (MMPs) and interleukin 1 (IL-1) are implicated in inflammation and tissue destruction, where IL-1 is a potent stimulator of connective tissue cells to produce the extracellular matrix-degrading MMPs. Here, we report that IL-1beta, but not IL-1alpha, is degraded by MMP-1 (in...

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Bibliographic Details
Main Authors:	Ito, A, Mukaiyama, A, Itoh, Y, Nagase, H, Thogersen, I, Enghild, J, Sasaguri, Y, Mori, Y
Format:	Journal article
Language:	English
Published:	1996

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