Antisense-derived HIV-1 cryptic epitopes are not major drivers of viral evolution during the acute phase of infection

Antisense-derived HIV-1 cryptic epitopes are not major drivers of viral evolution during the acute phase of infection

While prior studies have demonstrated that CD8 T cell responses to cryptic epitopes (CE) are readily detectable during HIV-1 infection, their ability to drive escape mutations following acute infection is unknown. We predicted 66 CE in a Zambian acute infection cohort based on escape mutations occur...

Полное описание

Библиографические подробности
Главные авторы:	Peng, B, Carlson, J, Liu, M, Gao, F, Goonetilleke, N, McMichael, A, Borrow, P, Gilmour, J, Heath, S, Hunter, E, Bansal, A, Goepfert, P
Формат:	Journal article
Язык:	English
Опубликовано:	American Society for Microbiology 2018

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