Characterisation of 2-oxoglutarate- and fe(II)-dependent oxygenases targeting the protein synthesis apparatus

Characterisation of 2-oxoglutarate- and fe(II)-dependent oxygenases targeting the protein synthesis apparatus

<p>Members of the 2-oxoglutarate (2OG)- and Fe(II)-dependent oxygenase (2OG oxygenase) superfamily catalyse a wide range of oxidative reactions in biology. 2OG oxygenases require Fe(II) and atmospheric oxygen for their activity, and couple substrate oxidation with the decarboxylation of 2OG in...

Descrizione completa

Dettagli Bibliografici
Autore principale:	Feng, T
Altri autori:	Ratcliffe, P
Natura:	Tesi
Lingua:	English
Pubblicazione:	2014
Soggetti:	Cell Biology Biochemistry

Documenti analoghi

Kinetic and mechanistic studies of oxygen sensing Fe(II)/2-oxoglutarate dependent oxygenases
di: Tarhonskaya, H
Pubblicazione: (2014)

NMR studies on 2-oxoglutarate oxygenases
di: Leung, IKH
Pubblicazione: (2013)

Crystallographic studies on 2-oxoglutarate dependent oxygenases
di: Aik, WS
Pubblicazione: (2014)

Functional and inhibition studies on 2-oxoglutarate-dependent oxygenases
di: Thalhammer, A
Pubblicazione: (2012)

2-oxoglutarate-dependent oxygenases
di: Islam, M, et al.
Pubblicazione: (2018)

Mechanistic studies on 2-oxoglutarate dependent oxygenases
di: Szollossi, A
Pubblicazione: (2012)

Interplay between 2-oxoglutarate oxygenases and cancer: studies on the aspartyl/asparaginyl-beta-hydroxylase
di: Pfeffer, I
Pubblicazione: (2014)

Identification of inhibitors for a family of human oxoglutarate-dependent oxygenases
di: Nowak, R
Pubblicazione: (2015)

Structural characterisation of calnexin cycle components and assessment as antiviral targets
di: Hill, J
Pubblicazione: (2018)

Inhibition of 2-oxoglutarate dependent oxygenases.
di: Rose, N, et al.
Pubblicazione: (2011)

Structural and biochemical characterisation of human integral membrane proteins regarded as potential therapeutic targets
di: da Costa Cabral Gomes Páscoa, T
Pubblicazione: (2022)

Mechanistic studies on 2-oxoglutarate dependent oxygenases
di: Schofield, C, et al.
Pubblicazione: (1999)

Dynamic combinatorial mass spectrometry for 2-oxoglutarate oxygenase inhibition
di: Demetriades, M
Pubblicazione: (2013)

Bi-directional regulation of type I interferon signaling by heme oxygenase-1
di: Miaomiao Wu, et al.
Pubblicazione: (2024-03-01)

Structural studies on human 2-oxoglutarate dependent oxygenases.
di: McDonough, M, et al.
Pubblicazione: (2010)

Autocatalysed oxidative modifications to 2-oxoglutarate dependent oxygenases
di: Mantri, M, et al.
Pubblicazione: (2012)

Autocatalysed oxidative modifications to 2-oxoglutarate dependent oxygenases
di: Mantri, M, et al.
Pubblicazione: (2012)

Autocatalysed oxidative modifications to 2-oxoglutarate dependent oxygenases.
di: Mantri, M, et al.
Pubblicazione: (2012)

Targeted dephosphorylation of SMAD3 as an approach to impede TGF-β signaling
di: Abigail Brewer, et al.
Pubblicazione: (2024-08-01)

Identification and characterisation of alternative forms of SETD2/HYPB (SET domain-containing protein 2 / Huntingtin yeast partner B)
di: Lee, BM
Pubblicazione: (2011)

Cellular models for characterisation of MINA53, a 2-oxoglutarate-dependent dioxygenase
di: Zayer, A
Pubblicazione: (2012)

A fluorescence-based assay for 2-oxoglutarate-dependent oxygenases.
di: McNeill, L, et al.
Pubblicazione: (2005)

Local activation of focal adhesion kinase orchestrates the positioning of presynaptic scaffold proteins and Ca2+ channel function to control glucose dependent insulin secretion
di: Hallahan, N, et al.
Pubblicazione: (2021)

The nucleolus functions as the compartment for histone H2B protein degradation
di: Yanping Liu, et al.
Pubblicazione: (2021-04-01)

Roles of oxygenases in nucleic acid modification
di: Bagg, E
Pubblicazione: (2011)

Role of structural dynamics in selectivity and mechanism of non-heme Fe(II) and 2-oxoglutarate-dependent oxygenases involved in DNA repair
di: Waheed, SO, et al.
Pubblicazione: (2020)

Role of Structural Dynamics in Selectivity and Mechanism of Non-heme Fe(II) and 2‑Oxoglutarate-Dependent Oxygenases Involved in DNA Repair
di: Sodiq O. Waheed, et al.
Pubblicazione: (2020-05-01)

iTAG an optimized IMiD-induced degron for targeted protein degradation in human and murine cells
di: Habib Bouguenina, et al.
Pubblicazione: (2023-07-01)

Structural and mechanistic studies on 2-oxoglutarate-dependent oxygenases and related enzymes.
di: Schofield, C, et al.
Pubblicazione: (1999)

Exploring links between 2-oxoglutarate-dependent oxygenases and Alzheimer's disease
di: Liu, H, et al.
Pubblicazione: (2022)

Protein phosphatase 6 function and regulation throughout the cell cycle
di: Ahel, J
Pubblicazione: (2018)

In situ modeling of acquired resistance to RTK/RAS-pathway-targeted therapies
di: Nancy E. Sealover, et al.
Pubblicazione: (2024-01-01)

Induction of nerve growth factor by phorbol 12-myristate 13-acetate is dependent upon the mitogen activated protein kinase pathway
di: Justin B. Davis, et al.
Pubblicazione: (2018-05-01)

Novel inverse agonists for the orphan G protein-coupled receptor 6
di: Alyssa S. Laun, et al.
Pubblicazione: (2018-11-01)

The role of iron and 2-oxoglutarate oxygenases in signalling.
di: Hewitson, K, et al.
Pubblicazione: (2003)

Expanding chemical biology of 2-oxoglutarate oxygenases.
di: Loenarz, C, et al.
Pubblicazione: (2008)

Role of mutual information for predicting contact residues in proteins
di: Gomes, M
Pubblicazione: (2012)

Mechanisms of TonB-dependent protein import in Pseudomonas aeruginosa
di: Goult, J
Pubblicazione: (2021)

The potential of 2-oxoglutarate oxygenases acting on nucleic acids as therapeutic targets
di: Thalhammer, A, et al.
Pubblicazione: (2012)

The potential of 2-oxoglutarate oxygenases acting on nucleic acids as therapeutic targets
di: Thalhammer, A, et al.
Pubblicazione: (2012)