Characterisation of 2-oxoglutarate- and fe(II)-dependent oxygenases targeting the protein synthesis apparatus

Characterisation of 2-oxoglutarate- and fe(II)-dependent oxygenases targeting the protein synthesis apparatus

<p>Members of the 2-oxoglutarate (2OG)- and Fe(II)-dependent oxygenase (2OG oxygenase) superfamily catalyse a wide range of oxidative reactions in biology. 2OG oxygenases require Fe(II) and atmospheric oxygen for their activity, and couple substrate oxidation with the decarboxylation of 2OG in...

Полное описание

Библиографические подробности
Главный автор:	Feng, T
Другие авторы:	Ratcliffe, P
Формат:	Диссертация
Язык:	English
Опубликовано:	2014
Предметы:	Cell Biology Biochemistry

Схожие документы

Kinetic and mechanistic studies of oxygen sensing Fe(II)/2-oxoglutarate dependent oxygenases
по: Tarhonskaya, H
Опубликовано: (2014)

NMR studies on 2-oxoglutarate oxygenases
по: Leung, IKH
Опубликовано: (2013)

Crystallographic studies on 2-oxoglutarate dependent oxygenases
по: Aik, WS
Опубликовано: (2014)

Functional and inhibition studies on 2-oxoglutarate-dependent oxygenases
по: Thalhammer, A
Опубликовано: (2012)

Mechanistic studies on 2-oxoglutarate dependent oxygenases
по: Szollossi, A
Опубликовано: (2012)

2-oxoglutarate-dependent oxygenases
по: Islam, M, и др.
Опубликовано: (2018)

Interplay between 2-oxoglutarate oxygenases and cancer: studies on the aspartyl/asparaginyl-beta-hydroxylase
по: Pfeffer, I
Опубликовано: (2014)

Structural characterisation of calnexin cycle components and assessment as antiviral targets
по: Hill, J
Опубликовано: (2018)

Identification of inhibitors for a family of human oxoglutarate-dependent oxygenases
по: Nowak, R
Опубликовано: (2015)

Inhibition of 2-oxoglutarate dependent oxygenases.
по: Rose, N, и др.
Опубликовано: (2011)

Structural and biochemical characterisation of human integral membrane proteins regarded as potential therapeutic targets
по: da Costa Cabral Gomes Páscoa, T
Опубликовано: (2022)

Mechanistic studies on 2-oxoglutarate dependent oxygenases
по: Schofield, C, и др.
Опубликовано: (1999)

Dynamic combinatorial mass spectrometry for 2-oxoglutarate oxygenase inhibition
по: Demetriades, M
Опубликовано: (2013)

Bi-directional regulation of type I interferon signaling by heme oxygenase-1
по: Miaomiao Wu, и др.
Опубликовано: (2024-03-01)

Structural studies on human 2-oxoglutarate dependent oxygenases.
по: McDonough, M, и др.
Опубликовано: (2010)

Autocatalysed oxidative modifications to 2-oxoglutarate dependent oxygenases
по: Mantri, M, и др.
Опубликовано: (2012)

Autocatalysed oxidative modifications to 2-oxoglutarate dependent oxygenases
по: Mantri, M, и др.
Опубликовано: (2012)

Autocatalysed oxidative modifications to 2-oxoglutarate dependent oxygenases.
по: Mantri, M, и др.
Опубликовано: (2012)

Targeted dephosphorylation of SMAD3 as an approach to impede TGF-β signaling
по: Abigail Brewer, и др.
Опубликовано: (2024-08-01)

Identification and characterisation of alternative forms of SETD2/HYPB (SET domain-containing protein 2 / Huntingtin yeast partner B)
по: Lee, BM
Опубликовано: (2011)

Cellular models for characterisation of MINA53, a 2-oxoglutarate-dependent dioxygenase
по: Zayer, A
Опубликовано: (2012)

A fluorescence-based assay for 2-oxoglutarate-dependent oxygenases.
по: McNeill, L, и др.
Опубликовано: (2005)

Local activation of focal adhesion kinase orchestrates the positioning of presynaptic scaffold proteins and Ca2+ channel function to control glucose dependent insulin secretion
по: Hallahan, N, и др.
Опубликовано: (2021)

The nucleolus functions as the compartment for histone H2B protein degradation
по: Yanping Liu, и др.
Опубликовано: (2021-04-01)

Roles of oxygenases in nucleic acid modification
по: Bagg, E
Опубликовано: (2011)

Role of structural dynamics in selectivity and mechanism of non-heme Fe(II) and 2-oxoglutarate-dependent oxygenases involved in DNA repair
по: Waheed, SO, и др.
Опубликовано: (2020)

Role of Structural Dynamics in Selectivity and Mechanism of Non-heme Fe(II) and 2‑Oxoglutarate-Dependent Oxygenases Involved in DNA Repair
по: Sodiq O. Waheed, и др.
Опубликовано: (2020-05-01)

iTAG an optimized IMiD-induced degron for targeted protein degradation in human and murine cells
по: Habib Bouguenina, и др.
Опубликовано: (2023-07-01)

In situ modeling of acquired resistance to RTK/RAS-pathway-targeted therapies
по: Nancy E. Sealover, и др.
Опубликовано: (2024-01-01)

Protein phosphatase 6 function and regulation throughout the cell cycle
по: Ahel, J
Опубликовано: (2018)

Structural and mechanistic studies on 2-oxoglutarate-dependent oxygenases and related enzymes.
по: Schofield, C, и др.
Опубликовано: (1999)

Exploring links between 2-oxoglutarate-dependent oxygenases and Alzheimer's disease
по: Liu, H, и др.
Опубликовано: (2022)

Induction of nerve growth factor by phorbol 12-myristate 13-acetate is dependent upon the mitogen activated protein kinase pathway
по: Justin B. Davis, и др.
Опубликовано: (2018-05-01)

Novel inverse agonists for the orphan G protein-coupled receptor 6
по: Alyssa S. Laun, и др.
Опубликовано: (2018-11-01)

Role of mutual information for predicting contact residues in proteins
по: Gomes, M
Опубликовано: (2012)

The role of iron and 2-oxoglutarate oxygenases in signalling.
по: Hewitson, K, и др.
Опубликовано: (2003)

Expanding chemical biology of 2-oxoglutarate oxygenases.
по: Loenarz, C, и др.
Опубликовано: (2008)

Mechanisms of TonB-dependent protein import in Pseudomonas aeruginosa
по: Goult, J
Опубликовано: (2021)

The potential of 2-oxoglutarate oxygenases acting on nucleic acids as therapeutic targets
по: Thalhammer, A, и др.
Опубликовано: (2012)

The potential of 2-oxoglutarate oxygenases acting on nucleic acids as therapeutic targets
по: Thalhammer, A, и др.
Опубликовано: (2012)